Changes in functional connectivity of motor zones in the course of treatment with a regent multimodal complex exoskeleton in neurorehabilitation of post-stroke patients
- Авторы: Saenko I.1,2, Morozova S.3, Zmeykina E.3, Konovalov R.3, Chervyakov A.3, Poydasheva A.3, Chernikova L.3, Suponeva N.3, Piradov M.3, Kozlovskaya I.1
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Учреждения:
- Institute of Medico-Biological Problems
- Center of Aerospace Medicine
- Neurology Research Center
- Выпуск: Том 42, № 1 (2016)
- Страницы: 54-60
- Раздел: Article
- URL: https://journals.rcsi.science/0362-1197/article/view/176536
- DOI: https://doi.org/10.1134/S036211971601014X
- ID: 176536
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Аннотация
The effect of a treatment course with a Regent multimodal complex exoskeleton (MCE) on the reorganization of cortical locomotor zones was studied in 14 patients with post-stroke hemiparesis, mainly in the chronic stage of the disease. Specific activation zones were identified prior to treatment in the primary sensorimotor and supplementary motor areas and the inferior parietal lobules of both affected and healthy hemispheres by functional magnetic resonance imaging (fMRI) used in a special passive sensorimotor paradigm. After a treatment course with the MCE, temporal characteristics of walking were found to improve, which was accompanied by a decrease in the activation zones of the inferior parietal lobules, especially in the healthy hemisphere, and a significant increase in the activation zones of the primary sensorimotor and supplementary motor areas. Significant changes in intrahemispheric and interhemispheric interactions were revealed by analyzing the functional connectivity of the zones under study before and after a course of treatment with the MCE.
Об авторах
I. Saenko
Institute of Medico-Biological Problems; Center of Aerospace Medicine
Автор, ответственный за переписку.
Email: isayenko@mail.ru
Россия, Moscow; Moscow
S. Morozova
Neurology Research Center
Email: isayenko@mail.ru
Россия, Moscow
E. Zmeykina
Neurology Research Center
Email: isayenko@mail.ru
Россия, Moscow
R. Konovalov
Neurology Research Center
Email: isayenko@mail.ru
Россия, Moscow
A. Chervyakov
Neurology Research Center
Email: isayenko@mail.ru
Россия, Moscow
A. Poydasheva
Neurology Research Center
Email: isayenko@mail.ru
Россия, Moscow
L. Chernikova
Neurology Research Center
Email: isayenko@mail.ru
Россия, Moscow
N. Suponeva
Neurology Research Center
Email: isayenko@mail.ru
Россия, Moscow
M. Piradov
Neurology Research Center
Email: isayenko@mail.ru
Россия, Moscow
I. Kozlovskaya
Institute of Medico-Biological Problems
Email: isayenko@mail.ru
Россия, Moscow