Biomaterials Based on Mixtures of Calcium Phosphates and Silicates: Investigation of Possible Production by Precipitation from Water Solutions

Abstract

Phase formation processes occurring in the open systems CaX₂–M₂HPO₄ /M₃PO₄–Na₂SiO₃–H₂O are analyzed. It is shown on the basis of the computed values of ΔG of crystallization that it is possible for mixtures of hydroxyapatite and calcium silicate to form in alkaline solutions. It is shown that the precipitation of calcium carbonate is just as likely in ‘wet’ synthesis in air. Ca₁₀(PO₄)₆(OH)₂, CaSiO₃, and CaCO₃ exhibit bioactivity, which makes it possible to use the system studied for the production of polyphase materials for bone tissue engineering.