Nocistatin and products of its proteolysis as dual modulators of type 3 acid-sensing ion channels (ASIC3) with an algesic and analgesic effect
- Autores: Osmakov D.1,2, Tarasova N.2, Nedorubov A.3, Palikov V.4, Palikova Y.4, Dyachenko I.4, Andreev Y.1,2, Kozlov S.1
-
Afiliações:
- Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- Institute of Molecular Medicine, Sechenov First Moscow State Medical University
- Institute of Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University
- Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- Edição: Volume 88, Nº 12 (2023)
- Páginas: 2531-2540
- Seção: Articles
- URL: https://journals.rcsi.science/0320-9725/article/view/249695
- DOI: https://doi.org/10.31857/S032097252312014X
- EDN: https://elibrary.ru/NQUQTQ
- ID: 249695
Citar
Resumo
Palavras-chave
Sobre autores
D. Osmakov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences;Institute of Molecular Medicine, Sechenov First Moscow State Medical University
Email: osmadim@gmail.com
117997 Moscow, Russia;119991 Moscow, Russia
N. Tarasova
Institute of Molecular Medicine, Sechenov First Moscow State Medical University119991 Moscow, Russia
A. Nedorubov
Institute of Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University119991 Moscow, Russia
V. Palikov
Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences142290 Pushchino, Russia
Y. Palikova
Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences142290 Pushchino, Russia
I. Dyachenko
Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences142290 Pushchino, Russia
Y. Andreev
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences;Institute of Molecular Medicine, Sechenov First Moscow State Medical University117997 Moscow, Russia;119991 Moscow, Russia
S. Kozlov
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: serg@ibch.ru
117997 Moscow, Russia
Bibliografia
- Chu, X.-P., and Xiong, Z.-G. (2012) Physiological and pathological functions of acid-sensing ion channels in the central nervous system, Curr. Drug Targets, 13, 263-271, doi: 10.2174/138945012799201685.
- Carattino, M. D., and Montalbetti, N. (2020) Acid-sensing ion channels in sensory signalling, Am. J. Physiol. Renal Physiol., 318, F531-F543, doi: 10.1152/ajprenal.00546.2019.
- Wemmie, J. A., Price, M. P., and Welsh, M. J. (2006) Acid-sensing ion channels: advances, questions and therapeutic opportunities, Trends Neurosci., 29, 578-586, doi: 10.1016/j.tins.2006.06.014.
- Deval, E., and Lingueglia, E. (2015) Acid-sensing ion channels and nociception in the peripheral and central nervous systems, Neuropharmacology, 94, 49-57, doi: 10.1016/j.neuropharm.2015.02.009.
- Schuhmacher, L.-N., and Smith, E. S. J. (2016) Expression of acid-sensing ion channels and selection of reference genes in mouse and naked mole rat, Mol. Brain, 9, 97, doi: 10.1186/s13041-016-0279-2.
- Boscardin, E., Alijevic, O., Hummler, E., Frateschi, S., and Kellenberger, S. (2016) The function and regulation of acid-sensing ion channels (ASICs) and the epithelial Na+ channel (ENaC): IUPHAR review 19, Br. J. Pharmacol., 173, 2671-2701, doi: 10.1111/bph.13533.
- Osmakov, D. I., Khasanov, T. A., Andreev, Y. A., Lyukmanova, E. N., and Kozlov, S. A. (2020) Animal, herb, and microbial toxins for structural and pharmacological study of acid-sensing ion channels, Front. Pharmacol., 11, 991, doi: 10.3389/fphar.2020.00991.
- Salinas, M., Lazdunski, M., and Lingueglia, E. (2009) Structural elements for the generation of sustained currents by the acid pain sensor ASIC3, J. Biol. Chem., 284, 31851-31859, doi: 10.1074/jbc.M109.043984.
- Deval, E., Noël, J., Lay, N., Alloui, A., Diochot, S., et al. (2008) ASIC3, a sensor of acidic and primary inflammatory pain, EMBO J., 27, 3047-3055, doi: 10.1038/emboj.2008.213.
- Yagi, J., Wenk, H. N., Naves, L. A., and McCleskey, E. W. (2006) Sustained currents through ASIC3 ion channels at the modest pH changes that occur during myocardial ischemia, Circ. Res., 99, 501-519, doi: 10.1161/01.RES.0000238388.79295.4c.
- Dulai, J. S., Smith, E. S. J., and Rahman, T. (2021) Acid-sensing ion channel 3: an analgesic target, Channels, 15, 94-127, doi: 10.1080/19336950.2020.1852831.
- Gründer, S., and Pusch, M. (2015) Biophysical properties of acid-sensing ion channels (ASICs), Neuropharmacology, 94, 9-18, doi: 10.1016/j.neuropharm.2014.12.016.
- Bohlen, C. J., Chesler, A. T., Sharif-Naeini, R., Medzihradszky, K. F., Zhou, S., et al. (2011) A heteromeric Texas coral snake toxin targets acid-sensing ion channels to produce pain, Nature, 479, 410-414, doi: 10.1038/nature10607.
- Yu, Y., Chen, Z., Li, W.-G., Cao, H., Feng, E.-G., et al. (2010) A nonproton ligand sensor in the acid-sensing ion channel, Neuron, 68, 61-72, doi: 10.1016/j.neuron.2010.09.001.
- Osmakov, D. I., Koshelev, S. G., Andreev, Y. A., Dubinnyi, M. A., Kublitski, V. S., et al. (2018) Proton-independent activation of acid-sensing ion channel 3 by an alkaloid, lindoldhamine, from Laurus nobilis, Br. J. Pharmacol., 175, 924-937, doi: 10.1111/bph.14134.
- Alijevic, O., and Kellenberger, S. (2012) Subtype-specific modulation of acid-sensing ion channel (ASIC) function by 2-guanidine-4-methylquinazoline, J. Biol. Chem., 287, 36059-36070, doi: 10.1074/jbc.M112.360487.
- Marra, S., Ferru-Clément, R., Breuil, V., Delaunay, A., Christin, M., et al. (2016) Non-acidic activation of pain-related acid-sensing ion channel 3 by lipids, EMBO J., 35, 414-428, doi: 10.15252/embj.201592335.
- Osmakov, D. I., Koshelev, S. G., Andreev, Y. A., and Kozlov, S. A. (2017) Endogenous isoquinoline alkaloids agonists of acid-sensing ion channel type 3, Front. Mol. Neurosci., 10, 282, doi: 10.3389/FNMOL.2017.00282.
- Osmakov, D. I., Koshelev, S. G., Ivanov, I. A., Andreev, Y. A., and Kozlov, S. A. (2019) Endogenous neuropeptide nocistatin is a direct agonist of acid-sensing ion channels (ASIC1, ASIC2 and ASIC3), Biomolecules, 9, 401, doi: 10.3390/BIOM9090401.
- Hallberg, M., and Nyberg, F. (2003) Neuropeptide conversion to bioactive fragments - an important pathway in neuromodulation, Curr. Protein Pept. Sci., 4, 31-44, doi: 10.2174/1389203033380313.
- Osmakov, D. I., Koshelev, S. G., Andreev, Y. A., Dyachenko, I. A., Bondarenko, D. A., et al. (2016) Conversed mutagenesis of an inactive peptide to ASIC3 inhibitor for active sites determination, Toxicon, 116, 11-16, doi: 10.1016/j.toxicon.2015.11.019.
- Hallberg, M. (2015) Neuropeptides: metabolism to bioactive fragments and the pharmacology of their receptors, Med. Res. Rev., 35, 464-519, doi: 10.1002/med.21323.
- Okuda-Ashitaka, E., and Ito, S. (2014) Nocistatin: milestone of one decade of research, Curr. Pharmaceut. Design, 21, 868-884, doi: 10.2174/1381612820666141027112451.
- Sakurada, C., Sakurada, S., Orito, T., Tan-No, K., and Sakurada, T. (2002) Degradation of nociceptin (orphanin FQ) by mouse spinal cord synaptic membranes is triggered by endopeptidase-24.11: an in vitro and in vivo study, Biochem. Pharmacol., 64, 1293-1303, doi: 10.1016/S0006-2952(02)01295-9.
- Terenius, L., Sandin, J., and Sakurada, T. (2000) Nociceptin/orphanin FQ metabolism and bioactive metabolites, Peptides, 21, 919-922, doi: 10.1016/S0196-9781(00)00228-X.
- Montiel, J. L., Cornille, F., Roques, B. P., and Noble, F. (1997) Nociceptin/orphanin FQ metabolism: role of aminopeptidase and endopeptidase 24.15, J. Neurochem., 68, 354-361, doi: 10.1046/j.1471-4159.1997.68010354.x.
- Mentlein, R., and Struckhoff, G. (1989) Purification of two dipeptidyl aminopeptidases II from rat brain and their action on proline-containing neuropeptides, J. Neurochem., 52, 1284-1293, doi: 10.1111/j.1471-4159.1989.tb01877.x.
- Kozlov, S. A., and Grishin, E. V. (2007) The universal algorithm of maturation for secretory and excretory protein precursors, Toxicon, 49, 721-726, doi: 10.1016/j.toxicon.2006.11.007.
- Erdös, E. G., and Skidgel, R. A. (1989) Neutral endopeptidase 24.11 (enkephalinase) and related regulators of peptide hormones, FASEB J., 3, 145-151, doi: 10.1096/fasebj.3.2.2521610.
- Wu, J., Liu, T. T., Zhou, Y. M., Qiu, C. Y., Ren, P., et al. (2017) Sensitization of ASIC3 by proteinase-activated receptor 2 signaling contributes to acidosis-induced nociception, J. Neuroinflammation, 14, 150, doi: 10.1186/s12974-017-0916-4.
- Deval, E., Gasull, X., Noël, J., Salinas, M., Baron, A., et al. (2010) Acid-sensing ion channels (ASICs): pharmacology and implication in pain, Pharmacol. Ther., 128, 549-558, doi: 10.1016/j.pharmthera.2010.08.006.
- Gründer, S., Ramírez, A. O., and Jékely, G. (2023) Neuropeptides and degenerin/epithelial Na+ channels: a relationship from mammals to cnidarians, J. Physiol., 601, 1583-1595, doi: 10.1113/JP282309.
- Vick, J. S., and Askwith, C. C. (2015) ASICs and neuropeptides, Neuropharmacology, 94, 36-41, doi: 10.1016/j.neuropharm.2014.12.012.
- Borg, C. B., Braun, N., Heusser, S. A., Bay, Y., Weis, D., et al. (2020) Mechanism and site of action of big dynorphin on ASIC1a (supplementary), Proc. Natl. Acad. Sci. USA, 117, 7447-7454, doi: 10.1073/pnas.1919323117.
- Kuspiel, S., Wiemuth, D., and Gründer, S. (2021) The neuropeptide nocistatin is not a direct agonist of acid-sensing ion channel 1a (ASIC1a), Biomolecules, 11, 571, doi: 10.3390/biom11040571.