Academician E.M. Kreps – founder оf the science of evolutionary biochemistry of brain lipids

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The article is dedicated to the founder of the evolutionary biochemistry of brain lipids, Evgeniy Mikhailovich Kreps, a remarkable scientist and person, academician, who for many years headed the Department of Physiology of the USSR Academy of Sciences and the Sechenov Institute of Evolutionary Physiology and Biochemistry of the USSR Academy of Sciences. The authors consider some stages of the scientific biography of E.M. Kreps, analyze the main results of his many years of work on studying the composition of complex brain lipids in representatives of all classes of vertebrates and some invertebrates. The authors made an attempt to give a modern assessment and interpretation of the patterns of changes in the composition of phospholipids, cerebrosides, gangliosides and their fatty acid radicals discovered by E.M. Kreps, associated with the complication of the organization of the central nervous system during evolution.

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作者简介

R. Parnova

Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences

编辑信件的主要联系方式.
Email: rimma_parnova@mail.ru
俄罗斯联邦, St. Petersburg, 194223

M. Firsov

Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences

Email: michael.firsov@gmail.com
俄罗斯联邦, St. Petersburg, 194223

参考

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2. Fig. 1. E.M. Kreps in his office, Leningrad, 1984.

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3. Fig. 2. E.M. Kreps at his dacha surrounded by colleagues on his birthday, May 1, 1984.

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4. Fig. 3. Murmansk Marine Biological Station, Aleksandrovsk-on-Murman, 1925 (photo from Alexandra Goryashko’s website, https://www.littorina.info).

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5. Fig. 4. Expeditionary vessel “Vityaz” (photo from the website https://world-ocean.ru/vityaz/istoriya).

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6. Fig. 5. E.M. Kreps and staff of the Laboratory of Neurochemistry, I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Leningrad, 1977.

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7. Fig. 6. Monograph by E.M. Kreps “Lipids of Cell Membranes” with the subtitle “Evolution of Brain Lipids. Adaptive Function of Lipids”.

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8. Fig. 7. Structural formula of cerebrosides and sulfocerebrosides.

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9. Fig. 8. Structural formula of ganglioside.

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10. Fig. 9. E.M. Kreps at the monument to L.A. Orbeli in front of the building of the I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Leningrad, 1985.

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