Thirty years after the Chernobyl accident: Molecular genetic mechanisms of carcinogenesis of the thyroid gland
- Authors: Tronko N.D.1, Pushkarev V.M.1
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Affiliations:
- Komisarenko Institute of Endocrinology and Metabolism
- Issue: Vol 50, No 6 (2016)
- Pages: 366-371
- Section: Article
- URL: https://journals.rcsi.science/0095-4527/article/view/173489
- DOI: https://doi.org/10.3103/S0095452716060098
- ID: 173489
Cite item
Abstract
The review presents data on the basic molecular genetic mechanisms of formation of papillary thyroid carcinoma. The participation of ionizing radiation in the cancer pathogenesis was analyzed. The role of tumor microenvironment, inflammation, and nuclear transcription factor NF-κB in the initiation and development of papillary thyroid carcinoma was shown.
About the authors
N. D. Tronko
Komisarenko Institute of Endocrinology and Metabolism
Email: pushkarev.vm@gmail.com
Ukraine, Kyiv, 04114
V. M. Pushkarev
Komisarenko Institute of Endocrinology and Metabolism
Author for correspondence.
Email: pushkarev.vm@gmail.com
Ukraine, Kyiv, 04114