125 years of virology and ascent of biotechnologies based on viral expressio
- Authors: Giritch A.1, Klimyuk V.2, Gleba Y.1
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Affiliations:
- Nomad Bioscience GmbH
- Icon Genetics GmbH
- Issue: Vol 51, No 2 (2017)
- Pages: 87-102
- Section: Article
- URL: https://journals.rcsi.science/0095-4527/article/view/173567
- DOI: https://doi.org/10.3103/S0095452717020037
- ID: 173567
Cite item
Abstract
The study of viruses lasts for more than a century since their discovery in 1892. In recent decades, viruses are also being actively exploited as a biotechnological tool. Plant-virus-driven transient expression of heterologous proteins is an actively developing production platform; it is the basis of several industrial processes that are currently being used for the production of multiple recombinant proteins. Viral vectors have also become useful tools for research. Viral vectors delivered by Agrobacterium (magnifection) provide for high protein yield, rapid scale up and fast manufacturing. In this review, we explore modern approaches for biotechnological production of recombinant proteins in plants using viral vectors.
About the authors
A. Giritch
Nomad Bioscience GmbH
Email: gleba@nomadbioscience.com
Germany, Weinbergweg 22, Halle, 06120
V. Klimyuk
Icon Genetics GmbH
Email: gleba@nomadbioscience.com
Germany, Weinbergweg 22, Halle, 06120
Y. Gleba
Nomad Bioscience GmbH
Author for correspondence.
Email: gleba@nomadbioscience.com
Germany, Weinbergweg 22, Halle, 06120