电邮这篇文章 Peptide Derivatives of 1,2-Dihydro-3-Methyl-2-Oxoquinoxaline-6-Carboxylic Acid: Synthesis and Evaluation of Antimicrobial, Antifungal and Antiviral Potential
- 作者: Chaudhary S.1,2, Kumar S.2, Tarazi H.1
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隶属关系:
- College of Pharmacy, University of Sharjah
- School of Pharmaceutical Sciences, IFTM University
- 期: 卷 50, 编号 5 (2016)
- 页面: 331-338
- 栏目: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244388
- DOI: https://doi.org/10.1007/s11094-016-1447-5
- ID: 244388
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详细
1,2-dihydro-3-methyl-2-oxoquinoxaline-6-carboxylic acid (S1) was prepared and coupled with various amino acid tri/tetrapeptide methyl esters to afford new quinoxalopeptide derivatives (S1a – S1i). The synthesized derivatives were characterized and screened for their antibacterial, antifungal and anthelmintic activity. Furthermore, molecular docking study revealed their potential in targeting human papillomavirus (HPV-16) E6 oncoprotein.
作者简介
Sachin Chaudhary
College of Pharmacy, University of Sharjah; School of Pharmaceutical Sciences, IFTM University
编辑信件的主要联系方式.
Email: Sachin.nehra84@gmail.com
阿拉伯联合酋长国, Sharjah, 27272; Lodhipur rajpoot, Delhi road, Moradabad, Uttar Pradesh, 244001
Sushil Kumar
School of Pharmaceutical Sciences, IFTM University
Email: Sachin.nehra84@gmail.com
印度, Lodhipur rajpoot, Delhi road, Moradabad, Uttar Pradesh, 244001
Hamadeh Tarazi
College of Pharmacy, University of Sharjah
Email: Sachin.nehra84@gmail.com
阿拉伯联合酋长国, Sharjah, 27272
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