Use of Micellar Electrokinetic Chromatography to Analyze Sesquiterpene Lactones from Laurus nobilis L.


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A micellar electrokinetic chromatographic method for quantitative determination of sesquiterpene lactones (costunolide and dehydrocostuslactone) from Laurus nobilis leaves was developed. It was shown that urea had to be added to the leading electrolyte in order to increase the analysis selectivity. The developed method was used to establish the costunolide and dehydrocostuslactone contents in various leaf samples as 0.5757 and 0.0399%, respectively, calculated per absolute dry raw material. The main validation characteristics of the developed method were also determined.

作者简介

S. Senchenko

Pyatigorsk Medical Pharmaceutical Institute, Branch of Volgograd State Medical University

Email: chem@folium.ru
俄罗斯联邦, Pyatigorsk, Stavropol Krai, 357532

N. Nasukhova

Pyatigorsk Medical Pharmaceutical Institute, Branch of Volgograd State Medical University

Email: chem@folium.ru
俄罗斯联邦, Pyatigorsk, Stavropol Krai, 357532

L. Agova

Pyatigorsk Medical Pharmaceutical Institute, Branch of Volgograd State Medical University

Email: chem@folium.ru
俄罗斯联邦, Pyatigorsk, Stavropol Krai, 357532

D. Konovalov

Pyatigorsk Medical Pharmaceutical Institute, Branch of Volgograd State Medical University

Email: chem@folium.ru
俄罗斯联邦, Pyatigorsk, Stavropol Krai, 357532


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