Modern Technologies for Synthesizing Drug Substances: Toward Highly Efficient Drug Production

详细

Implementation of new technologies for synthesizing drug substances, e.g., continuous-flow microreactor synthesis of active drug substances (ADS) and asymmetric synthesis of intermediates and ADS using enzymes created by gene engineering methods, is highly significant for localizing ADS production in Russia. The possibility of using the existing Russian scientific infrastructure for rapid implementation of domestic production of a new ADS portfolio with the least operating losses, maximum economic efficiency, and high competitiveness was demonstrated.