Отправить статью по E-mail Development and Validation of a Quantitative Determination Technique for Phenibut in Microcapsules
- Авторы: Polkovnikova Y.A.1, Koryanova K.N.2, Slivkin A.I.1, Tul’skaya U.A.1, Senchenko S.P.2
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Учреждения:
- Voronezh State University
- Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
- Выпуск: Том 52, № 9 (2018)
- Страницы: 803-807
- Раздел: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245477
- DOI: https://doi.org/10.1007/s11094-018-1904-4
- ID: 245477
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Аннотация
A capillary electrophoresis technique for quantitative determination of phenibut in microcapsules was developed and validated. Rather high efficiencies (~200,000 theoretical plates) and the required resolution (Rs ≥ 1.5) were attained using sodium tetraborate decahydrate solution (10 mM) at pH 9.2 as the supporting electrolyte. Validation of the technique showed that it was specific and complied with requirements of the SP XIIIth Ed. with respect to analytical range and linearity.
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Yu. Polkovnikova
Voronezh State University
Автор, ответственный за переписку.
Email: juli-polk@mail.ru
Россия, Studencheskaya St., Voronezh, 394006
K. Koryanova
Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
Email: juli-polk@mail.ru
Россия, 11 Kalinina Prosp., Pyatigorsk, Stavropol’skii Krai, 357532
A. Slivkin
Voronezh State University
Email: juli-polk@mail.ru
Россия, Studencheskaya St., Voronezh, 394006
U. Tul’skaya
Voronezh State University
Email: juli-polk@mail.ru
Россия, Studencheskaya St., Voronezh, 394006
S. Senchenko
Pyatigorsk Medico-Pharmaceutical Institute, Branch of Volgograd State Medical University
Email: juli-polk@mail.ru
Россия, 11 Kalinina Prosp., Pyatigorsk, Stavropol’skii Krai, 357532
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