Synthesis and Anticonvulsive Activity of 5-Pyrrolidin-1-Ylpyrano[4″,3″:4′,5′]Pyrido-3′,2′:4,5]Thieno[3,2-D]Pyrimidine Derivatives
- Авторы: Dashyan S.1, Paronikyan E.1, Noravyan A.1, Paronikyan R.1
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Учреждения:
- Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
- Выпуск: Том 50, № 4 (2016)
- Страницы: 221-225
- Раздел: Search for New Drugs
- URL: https://journals.rcsi.science/0091-150X/article/view/244347
- DOI: https://doi.org/10.1007/s11094-016-1426-x
- ID: 244347
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Аннотация
A method for preparing the amino, alkoxy, and alkylsulfanyl derivatives of pyrano[4″,3″:4′,5′]pyrido-[3′,2′:4,5]thieno[3,2-d]pyrimidines based on 8-chloro-2,2-dimethyl-5-pyrrolidin-1-yl-1,4-dihydro-2H-pyrano[4″,3″:4′,5′]pyrido[3′,2′:4,5]thieno[3,2-d]pyrimidine was developed. The anticonvulsant activity of the compounds synthesized here was investigated.
Об авторах
Sh. Dashyan
Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: chem@folium.ru
Армения, Yerevan
E. Paronikyan
Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: chem@folium.ru
Армения, Yerevan
A. Noravyan
Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: chem@folium.ru
Армения, Yerevan
R. Paronikyan
Institute of Fine Organic Chemistry, Science and Technology Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: chem@folium.ru
Армения, Yerevan