Antioxidant and Antiradical Activity of Drugs Intended for Treating Ophthalmic Disorders

A. V. Ivanova; E. L. Gerasimova; E. R. Gazizullina; Ya. A. Okulova; A. I. Matern; V. L. Rusinov

doi:10.1007/s11094-018-1883-5

Antioxidant and Antiradical Activity of Drugs Intended for Treating Ophthalmic Disorders

Autores: Ivanova A.¹, Gerasimova E.¹, Gazizullina E.¹, Okulova Y.¹, Matern A.¹, Rusinov V.¹
Afiliações:
1. Institute of Chemical Technology, B. N. Yeltsin Ural Federal University
Edição: Volume 52, Nº 8 (2018)
Páginas: 694-699
Seção: Article
URL: https://journals.rcsi.science/0091-150X/article/view/245415
DOI: https://doi.org/10.1007/s11094-018-1883-5
ID: 245415

Citar

Texto integral

Acesso aberto
Acesso é fechado

Acesso está concedido
Acesso é fechado

Somente assinantes

Resumo
Sobre autores
Bibliografia
Estatísticas

Resumo

Dosage forms intended for ophthalmic use with declared and potential antioxidant properties were investigated. Antioxidant activity was determined using potentiometry with potassium hexacyanoferrate (III) as the oxidant. Antiradical activity was studied using the stable radical 2,2-diphenyl-1-picrylhydrazyl. The reaction half-lives of the investigated dosage forms were determined. Ratios of the experimental antioxidant activity to the content of main active ingredient were assessed.