Benzimidazole Ring System as a Privileged Template for Anticancer Agents
- Autores: Kanwal A.1, Saddique F.1, Aslam S.2, Ahmad M.1, Zahoor A.1, Mohsin N.3
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Afiliações:
- Department of Chemistry, Government College University
- Department of Chemistry, Government College Women University
- Faculty of Pharmaceutical Sciences, Government College University
- Edição: Volume 51, Nº 12 (2018)
- Páginas: 1068-1077
- Seção: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244916
- DOI: https://doi.org/10.1007/s11094-018-1742-4
- ID: 244916
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Resumo
Cancer still remains a continued threat for human race in the 21st century. It is the major cause of human casualties globally and is thus, a hot topic of research in medicinal laboratories. Scientists are striving to find selective anticancer agents having low toxicity for normal human cells. Heterocyclic ring systems play key role as templates/pharmacophores for various drugs, and benzimidazole ring is especially important for its anticancer derivatives. In this review article, we have focused on the structural features of anticancer derivatives based on benzimidazole ring system. It highlights various benzimidazole-based anticancer compounds which have been developed in recent years.
Sobre autores
Afshan Kanwal
Department of Chemistry, Government College University
Email: Matloob.Ahmad@gcuf.edu.pk
Paquistão, Faisalabad, 38000
Furqan Saddique
Department of Chemistry, Government College University
Email: Matloob.Ahmad@gcuf.edu.pk
Paquistão, Faisalabad, 38000
Sana Aslam
Department of Chemistry, Government College Women University
Email: Matloob.Ahmad@gcuf.edu.pk
Paquistão, Faisalabad, 38000
Matloob Ahmad
Department of Chemistry, Government College University
Autor responsável pela correspondência
Email: Matloob.Ahmad@gcuf.edu.pk
Paquistão, Faisalabad, 38000
Ameer Zahoor
Department of Chemistry, Government College University
Email: Matloob.Ahmad@gcuf.edu.pk
Paquistão, Faisalabad, 38000
Noor-ul-Amin Mohsin
Faculty of Pharmaceutical Sciences, Government College University
Email: Matloob.Ahmad@gcuf.edu.pk
Paquistão, Faisalabad, 38000