Enviar artigo por via de e-mail Convenient Four-Step Synthesis of H-Pyr-His-Trp-OH, a Key Tripeptide Intermediate for the Production of Synthetic Gonadoliberin Agonists
- Autores: Balaev A.N.1, Okhmanovich K.A.1, Fedorov V.E.1
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Afiliações:
- Pharm-Sintez Co., 8 2nd Roshchinskii Proezd
- Edição: Volume 50, Nº 3 (2016)
- Páginas: 192-194
- Seção: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244342
- DOI: https://doi.org/10.1007/s11094-016-1421-2
- ID: 244342
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Resumo
An effective four-step synthesis of the tripeptide H-Pyr-His-Trp-OH that is used to produce synthetic gonadoliberin agonists was developed. The synthesis was carried out without adding and removing protecting groups and could produce the target compound with >98% purity.
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Sobre autores
A. Balaev
Pharm-Sintez Co., 8 2nd Roshchinskii Proezd
Email: chem@folium.ru
Rússia, Moscow, 115419
K. Okhmanovich
Pharm-Sintez Co., 8 2nd Roshchinskii Proezd
Email: chem@folium.ru
Rússia, Moscow, 115419
V. Fedorov
Pharm-Sintez Co., 8 2nd Roshchinskii Proezd
Email: chem@folium.ru
Rússia, Moscow, 115419
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