Enviar artigo por via de e-mail Arrhenius Kinetics As a Bioactivity Assessment Criterion for Drug Substances and Excipients
- Autores: Levitskaya O.V.1, Syroeshkin A.V.1, Pleteneva T.V.1
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Afiliações:
- Russian University of People’s Friendship, 8 Miklukho-Maklaya St.
- Edição: Volume 49, Nº 11 (2016)
- Páginas: 779-781
- Seção: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244291
- DOI: https://doi.org/10.1007/s11094-016-1370-9
- ID: 244291
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Resumo
Arrhenius kinetic principles, in particular, Ea values, were used to assess the biological activity of drug substances in aqueous solutions with different D/H ratios. The obtained activation energies indicated that deuterium-depleted solutions had lower toxicity and biological activity.
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Sobre autores
O. Levitskaya
Russian University of People’s Friendship, 8 Miklukho-Maklaya St.
Autor responsável pela correspondência
Email: titorovicholga@gmail.com
Rússia, Moscow, 117198
A. Syroeshkin
Russian University of People’s Friendship, 8 Miklukho-Maklaya St.
Email: titorovicholga@gmail.com
Rússia, Moscow, 117198
T. Pleteneva
Russian University of People’s Friendship, 8 Miklukho-Maklaya St.
Email: titorovicholga@gmail.com
Rússia, Moscow, 117198
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