Comparison of Quantitative Analytical Techniques for Dabigatran in Blood Plasma of Humans with Knee Replacements
- Авторлар: Kozlov A.V.1, Smirnov V.V.1, Sychev D.A.2, Bochkov P.O.3, Chistyakov V.V.4, Stepanova E.S.4, Makarenkova L.M.4
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Мекемелер:
- I. M. Sechenov First Moscow State Medical University (Sechenov University)
- Russian Medical Academy of Continuous Professional Education, Ministry of Health of the RF
- V. V. Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences
- Research and Education Center, Peoples’ Friendship University of Russia
- Шығарылым: Том 53, № 8 (2019)
- Беттер: 771-774
- Бөлім: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245993
- DOI: https://doi.org/10.1007/s11094-019-02077-x
- ID: 245993
Дәйексөз келтіру
Аннотация
Two different literature methods were used to compare the experimental efficacy and accuracy of dabigatran assays in blood of 30 patients with knee replacements. Blood plasma was collected from patients who underwent anticoagulant therapy and were administered the medicine at a dose of 220 mg. Residual and peak dabigatran concentrations were determined by HPLC-MS and HPLC-MS/MS.
Негізгі сөздер
Авторлар туралы
A. Kozlov
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Хат алмасуға жауапты Автор.
Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 119991
V. Smirnov
I. M. Sechenov First Moscow State Medical University (Sechenov University)
Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 119991
D. Sychev
Russian Medical Academy of Continuous Professional Education, Ministry of Health of the RF
Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 125993
P. Bochkov
V. V. Zakusov State Institute of Pharmacology, Russian Academy of Medical Sciences
Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 125315
V. Chistyakov
Research and Education Center, Peoples’ Friendship University of Russia
Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 117198
E. Stepanova
Research and Education Center, Peoples’ Friendship University of Russia
Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 117198
L. Makarenkova
Research and Education Center, Peoples’ Friendship University of Russia
Email: aleksei.kozlov1993@yandex.ru
Ресей, Moscow, 117198
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