Мақаланы E-mail арқылы жіберу Cytotoxicity of New Ferulic-Acid Derivatives on Human Colon Carcinoma (HCT116) Cells
- Авторлар: Bakholdina L.1,2, Markova A.3, Khlebnikov A.4, Sevodin V.1
-
Мекемелер:
- Biisk Technological Institute (Filial), I. I. Polzunov Altai State Technical University
- Institute for Problems of Chemical and Energetic Technologies, Siberian Branch, Russian Academy of Sciences
- A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
- National Research Tomsk Polytechnic University
- Шығарылым: Том 53, № 6 (2019)
- Беттер: 516-520
- Бөлім: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245839
- DOI: https://doi.org/10.1007/s11094-019-02030-y
- ID: 245839
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
A series of esters of ferulic acid and alcohols were synthesized and characterized structurally. All tested synthetic compounds were more cytotoxic against HCT116 cell line (human colon carcinoma) than ferulic acid. Benzyl and phenylethyl esters of ferulic acid were the most active compounds (IC50 = 0.0077 and 0.0065 g/L, respectively). Feruloylated wheat-bran oligosaccharides were less active than free ferulic acid against HCT116 tumor cells.
Авторлар туралы
L. Bakholdina
Biisk Technological Institute (Filial), I. I. Polzunov Altai State Technical University; Institute for Problems of Chemical and Energetic Technologies, Siberian Branch, Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: ljuba27@mail.ru
Ресей, 27 Trofimov St., Biisk, Altai Krai, 659305; Biisk, Altai Krai, 659322
A. Markova
A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences
Email: ljuba27@mail.ru
Ресей, Moscow, 119991
A. Khlebnikov
National Research Tomsk Polytechnic University
Email: ljuba27@mail.ru
Ресей, Tomsk, 634050
V. Sevodin
Biisk Technological Institute (Filial), I. I. Polzunov Altai State Technical University
Email: ljuba27@mail.ru
Ресей, 27 Trofimov St., Biisk, Altai Krai, 659305
