The Effects of Solvent Polarity on Analgesic and Anti-Inflammatory Activities of Securigera Securidaca (L.), Achillea Eriophora DC, and Portulaca Oleracea Extracts
- Авторлар: Ahmadi A.1, Khalili M.2, Salimi M.1, Mirsistani N.1, Niksirat A.3, Nazirzadeh S.4
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Мекемелер:
- Department of Chemistry, Faculty of Science, Karaj Branch, Islamic Azad University
- Neurophysiology Research Center, Shahed University
- Department of Chemistry, Faculty of Medicinal Chemistry, Tehran Medical Sciences, Islamic Azad University
- Department of Horticultural Science, Saveh Branch, Islamic Azad University
- Шығарылым: Том 53, № 3 (2019)
- Беттер: 248-263
- Бөлім: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245719
- DOI: https://doi.org/10.1007/s11094-019-01988-z
- ID: 245719
Дәйексөз келтіру
Аннотация
The effect of solvent polarity on bioactive extraction contents of three famous medicinal plants (Securigera securidaca, Portulaca oleracea and Achillea eriophora) with reported analgesic and anti-inflammatory activities was evaluated by GC-MS analysis. Pain and inflammation-lowering properties of all extracts were evaluated and compared to ibuprofen as well-known nonsteroidal anti-inflammatory drug (NSAID). The results indicated that, more extracted sterols, fatty acids, polyols (or alcohols), phenols, and flavonoids from S. securidaca and P. oleracea as well as antraquinone and terpenes from A. eriophora may be responsible for higher analgesic and anti-inflammatory activities of these herbal extracts. Carbon tetrachloride and chloroform (or dichloromethane) more effectively extract phytochemicals than do aqueous ethanol solutions, which can be related to higher solubility of these compounds in the former non-aqueous organic solvents.
Авторлар туралы
Abbas Ahmadi
Department of Chemistry, Faculty of Science, Karaj Branch, Islamic Azad University
Хат алмасуға жауапты Автор.
Email: a-ahmadi@kiau.ac.ir
Иран, Karaj
Mohsen Khalili
Neurophysiology Research Center, Shahed University
Email: a-ahmadi@kiau.ac.ir
Иран, Tehran
Maryam Salimi
Department of Chemistry, Faculty of Science, Karaj Branch, Islamic Azad University
Email: a-ahmadi@kiau.ac.ir
Иран, Karaj
Niloofar Mirsistani
Department of Chemistry, Faculty of Science, Karaj Branch, Islamic Azad University
Email: a-ahmadi@kiau.ac.ir
Иран, Karaj
Ayda Niksirat
Department of Chemistry, Faculty of Medicinal Chemistry, Tehran Medical Sciences, Islamic Azad University
Email: a-ahmadi@kiau.ac.ir
Иран, Tehran
Sommayeh Nazirzadeh
Department of Horticultural Science, Saveh Branch, Islamic Azad University
Email: a-ahmadi@kiau.ac.ir
Иран, Saveh