Assessment of the Acute Toxicity and Analgesic Activity of Ethyl-6-Amino-4-Aryl-5-Cyano-2,4-Dihydropyrano-2,3-C]-Pyrazole-3-Carboxylates


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Abstract

The acute toxicity and analgesic activity of compounds of the ethyl-6-amino-4-aryl-5-cyano-2,4-dihydropyrano[2,3-c]pyrazole-3-carboxylate series were investigated. Study compounds were found to be essentially nontoxic and to have analgesic activity.

About the authors

O. N. Gein

Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation

Email: geinvl48@mail.ru
Russian Federation, 2 Polevaya Street, Perm, 614990

T. M. Zamaraeva

Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation

Email: geinvl48@mail.ru
Russian Federation, 2 Polevaya Street, Perm, 614990

V. L. Gein

Perm State Pharmaceutical Academy, Ministry of Health of the Russian Federation

Author for correspondence.
Email: geinvl48@mail.ru
Russian Federation, 2 Polevaya Street, Perm, 614990


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