Enviar artigo por via de e-mail Synthesis and Antimicrobial Activity of 3-Phenyl-1-Methylquinolin-2-One Derivatives
- Autores: Elenich O.1, Lytvyn R.2, Blinder O.3, Skripskaya O.1, Lyavinets O.1, Pitkovych K.2, Obushak M.2, Yagodinets P.1
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Afiliações:
- Yuriy Fedkovych Chernivtsi National University
- Ivan Franko National University of Lviv
- L. I. Medved Research Center of Preventive Toxicology, Food and Chemical Safety, Department of Medical and Environmental Problems, Ministry of Health
- Edição: Volume 52, Nº 12 (2019)
- Páginas: 969-974
- Seção: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245563
- DOI: https://doi.org/10.1007/s11094-019-01935-y
- ID: 245563
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Resumo
A series of quaternary salts were obtained by reacting 3-(4-bromoacetylphenyl)-1-methylquinolin-2(1H)-one with Py, 4-methylpyridine, quinoline, benzo[f]quinoline, and triphenylphosphine. Derivatives of thiazole, imidazo[1,2-a]pyridine, and imidazo[1,2-a]pyrimidine were produced using dinucleophilic reagents. Several of the synthesized compounds possessed high antimicrobial activity, indicating that further research on this series of compounds was promising.
Sobre autores
O. Elenich
Yuriy Fedkovych Chernivtsi National University
Email: obushak@in.lviv.ua
Ucrânia, 25 Lesi Ukrainki St., Chernivtsi, 58012
R. Lytvyn
Ivan Franko National University of Lviv
Email: obushak@in.lviv.ua
Ucrânia, 6 Kirilla i Mefodiya St., Lviv, 79005
O. Blinder
L. I. Medved Research Center of Preventive Toxicology, Food and Chemical Safety, Department of Medical and Environmental Problems, Ministry of Health
Email: obushak@in.lviv.ua
Ucrânia, Ukraine, 30 Fedkovych St., Chernivtsi, 58022
O. Skripskaya
Yuriy Fedkovych Chernivtsi National University
Email: obushak@in.lviv.ua
Ucrânia, 25 Lesi Ukrainki St., Chernivtsi, 58012
O. Lyavinets
Yuriy Fedkovych Chernivtsi National University
Email: obushak@in.lviv.ua
Ucrânia, 25 Lesi Ukrainki St., Chernivtsi, 58012
Kh. Pitkovych
Ivan Franko National University of Lviv
Email: obushak@in.lviv.ua
Ucrânia, 6 Kirilla i Mefodiya St., Lviv, 79005
M. Obushak
Ivan Franko National University of Lviv
Autor responsável pela correspondência
Email: obushak@in.lviv.ua
Ucrânia, 6 Kirilla i Mefodiya St., Lviv, 79005
P. Yagodinets
Yuriy Fedkovych Chernivtsi National University
Email: obushak@in.lviv.ua
Ucrânia, 25 Lesi Ukrainki St., Chernivtsi, 58012
