Kinetics of One-Step Mepivacaine Synthesis on Polymers Containing Pd-Nanoparticles
- Authors: Abdullaev M.G.1
-
Affiliations:
- Dagestan State University
- Issue: Vol 52, No 10 (2019)
- Pages: 865-867
- Section: Drug Synthesis Methods and Manufacturing Technology
- URL: https://journals.rcsi.science/0091-150X/article/view/245515
- DOI: https://doi.org/10.1007/s11094-019-1917-7
- ID: 245515
Cite item
Abstract
The kinetic factors influencing the hydroacylation of 2,6-dimethylnitrobenzene in the presence of Pd nanoparticles bound to anion exchangers were studied. A general scheme for catalytic synthesis of mepivacaine was proposed based on the obtained kinetic data. The one-step synthesis of mepivacaine was demonstrated to be efficient on various Pd-containing polymer catalysts.
About the authors
M. G. Abdullaev
Dagestan State University
Author for correspondence.
Email: mahram-ivgu@rambler.ru
Russian Federation, Makhachkala, Dagestan