Microemulsions as Potential Bases for Formulating Modern Transdermal Therapeutics


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Abstract

Promising directions for the discovery of universal carriers for active pharmaceutical ingredients (APIs) are reviewed. Transdermal delivery of the APIs in medicines is attracting increasing attention from designers of drug formulations. A transdermal therapeutic system (TTS) is a dosage form for external use as controlled-release patches or films. TTSs are classified depending on the mode of API incorporation into several basic types such as reservoir, adhesive, matrix, and microreservoir. Methods for developing TTSs based on microemulsions are described in the review.

About the authors

G. N. Gil’deeva

I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation

Author for correspondence.
Email: gilgeln@gmail.com
Russian Federation, 8/2 Malaya Trubetskaya St., Moscow, 119991

V. I. Yurkov

MDA Ltd.

Email: gilgeln@gmail.com
Russian Federation, 1 Vasilisy Kozhinoi St., Floor 8, Office 803.6, Moscow, 121096


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