Email this article Synthesis and Biological Activity of 6-(1,3-Benzoxazol-2-Yl)-5-Methylthieno-[2,3-d]Pyrimidines
- Authors: Vlasov S.V.1, Kovalenko S.N.1, Osolodchenko T.P.2, Lenitskaya E.B.1, Chernykh V.P.1
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Affiliations:
- National University of Pharmacy
- I. I. Mechnikov Institute of Microbiology and Immunology, National Academy of Medical Sciences of Ukraine
- Issue: Vol 52, No 6 (2018)
- Pages: 510-514
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245290
- DOI: https://doi.org/10.1007/s11094-018-1850-1
- ID: 245290
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Abstract
An approach to the synthesis of new 6-(1,3-benzoxazol-2-yl)-5-methylthieno[2,3-d]pyrimidin-4(3H)-ones and their 4-thioanalogs was developed. Some of the synthesized compounds exhibited antimicrobial activity against strains of Bacillus subtilis bacteria and Candida albicans fungi.
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About the authors
S. V. Vlasov
National University of Pharmacy
Author for correspondence.
Email: sergiy.vlasov@gmail.com
Ukraine, 53 Pushkinskaya St., Kharkiv, 61002
S. N. Kovalenko
National University of Pharmacy
Email: sergiy.vlasov@gmail.com
Ukraine, 53 Pushkinskaya St., Kharkiv, 61002
T. P. Osolodchenko
I. I. Mechnikov Institute of Microbiology and Immunology, National Academy of Medical Sciences of Ukraine
Email: sergiy.vlasov@gmail.com
Ukraine, 14 – 16 Pushkinskaya St., Kharkiv, 61057
E. B. Lenitskaya
National University of Pharmacy
Email: sergiy.vlasov@gmail.com
Ukraine, 53 Pushkinskaya St., Kharkiv, 61002
V. P. Chernykh
National University of Pharmacy
Email: sergiy.vlasov@gmail.com
Ukraine, 53 Pushkinskaya St., Kharkiv, 61002
