Email this article Comparison of Spectrophotometric and Chromatographic (HPLC) Procedures for Determining 3-Phenethylrhodanine Drug Substance with Anticancer Activity
- Authors: Novozhilova N.E.1, Kutina N.N.1, Kharitonov Y.Y.2
-
Affiliations:
- Medbiopharm Innovation Company
- I. M. Sechenov First Moscow Medical University
- Issue: Vol 52, No 2 (2018)
- Pages: 156-158
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245042
- DOI: https://doi.org/10.1007/s11094-018-1782-9
- ID: 245042
Cite item
Open Access
Access granted
Subscription Access
Abstract
A comparison of spectrophotometric and chromatographic (HPLC) procedures for determining 3-phenethylrhodanine (cyclo-2-phenethyldithiocarbanoylacetic acid, CPET) drug substance using experimental and computational statistical methods showed that both methods had good precision and accuracy and could be recommended as equivalent alternative methods for quantitative determination of CPET drug substance.
About the authors
N. E. Novozhilova
Medbiopharm Innovation Company
Email: chem@folium.ru
Russian Federation, Obninsk, Kaluga Oblast, 249030
N. N. Kutina
Medbiopharm Innovation Company
Email: chem@folium.ru
Russian Federation, Obninsk, Kaluga Oblast, 249030
Yu. Ya. Kharitonov
I. M. Sechenov First Moscow Medical University
Email: chem@folium.ru
Russian Federation, Moscow
