Email this article Synthesis and Neurotropic Activity of New 7-Cyclohexyl-6,7,8,9-Tetrahydro-3H-Pyrazolo[3,4-c]-2,7-Naphthyridine-1,5-Diamines
- Authors: Sirakanyan S.N.1, Hakobyan E.K.1, Nikoghosyan A.G.1, Paronikyan R.G.1, Dzhagatspanyan I.A.1, Nazaryan I.M.1, Akopyan A.G.1, Hovakimyan A.A.1
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Affiliations:
- A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
- Issue: Vol 52, No 2 (2018)
- Pages: 108-111
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/245015
- DOI: https://doi.org/10.1007/s11094-018-1773-x
- ID: 245015
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Abstract
A method for synthesizing new tricyclic heterocyclic 7-cyclohexyl-6,7,8,9-tetrahydro-3H-pyrazolo- [3,4-c]-2,7-naphthyridine-1,5-diamines from 1,3-dichloro-7-cyclohexyl-5,6, 7,8-tetrahydro-2,7-naphthyridine-4-carbonitrile was elaborated. Investigation of the biological activity of the synthesized compounds showed that several of them exhibited pronounced neurotropic properties.
About the authors
S. N. Sirakanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Author for correspondence.
Email: shnnr@mail.ru
Armenia, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
E. K. Hakobyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Armenia, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
A. G. Nikoghosyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Armenia, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
R. G. Paronikyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Armenia, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
I. A. Dzhagatspanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Armenia, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
I. M. Nazaryan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Armenia, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
A. G. Akopyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Armenia, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
A. A. Hovakimyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Email: shnnr@mail.ru
Armenia, 26 Prosp. Azatutyan, 0014, Yerevan, 375014
