Experimental Antioxidant Activity of a β-Cyclodextrin – Histochrome Complex
- Авторы: Bikbov M.M.1, Nikitin N.A.1, Surkova V.K.1, Farkhutdinov R.R.2, Khalilov L.M.3, Tulyabaev A.R.3, Nikitina A.F.1, Fedoreev S.A.4, Mishchenko N.P.4
 - 
							Учреждения: 
							
- Ufa Eye Research Institute, Academy of Sciences of the Republic of Bashkortostan
 - Bashkir State Medical University, MH RF
 - Institute of Petrochemistry and Catalysis, Ufa Scientific Center, Russian Academy of Sciences
 - G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch, Russian Academy of Sciences
 
 - Выпуск: Том 51, № 11 (2018)
 - Страницы: 980-984
 - Раздел: Article
 - URL: https://journals.rcsi.science/0091-150X/article/view/244880
 - DOI: https://doi.org/10.1007/s11094-018-1727-3
 - ID: 244880
 
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Аннотация
A2:1 β-cyclodextrin – histochrome complex was synthesized based on a comparison with experimental studies of histochrome and showed antioxidant activity prolonged to 16 d as compared with 6 d for histochrome in tests of the duration of the in vitro antioxidant effect. PMR measurements proved that a β-cyclodextrin – histochrome complex formed. Computer modeling of the β-cyclodextrin–histochrome complex showed that the head-to-tail complex corresponded to the energy minimum.
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Об авторах
M. Bikbov
Ufa Eye Research Institute, Academy of Sciences of the Republic of Bashkortostan
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Ufa, Bashkortostan, 450008						
N. Nikitin
Ufa Eye Research Institute, Academy of Sciences of the Republic of Bashkortostan
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Ufa, Bashkortostan, 450008						
V. Surkova
Ufa Eye Research Institute, Academy of Sciences of the Republic of Bashkortostan
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Ufa, Bashkortostan, 450008						
R. Farkhutdinov
Bashkir State Medical University, MH RF
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Ufa, Bashkortostan, 450008						
L. Khalilov
Institute of Petrochemistry and Catalysis, Ufa Scientific Center, Russian Academy of Sciences
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Ufa, Bashkortostan, 450054						
A. Tulyabaev
Institute of Petrochemistry and Catalysis, Ufa Scientific Center, Russian Academy of Sciences
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Ufa, Bashkortostan, 450054						
A. Nikitina
Ufa Eye Research Institute, Academy of Sciences of the Republic of Bashkortostan
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Ufa, Bashkortostan, 450008						
S. Fedoreev
G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch, Russian Academy of Sciences
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Vladivostok, 690922						
N. Mishchenko
G. B. Elyakov Pacific Institute of Bioorganic Chemistry, Far-Eastern Branch, Russian Academy of Sciences
														Email: chem@folium.ru
				                					                																			                												                	Россия, 							Vladivostok, 690922						
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