Synthesis and Biological Activity of β-Aroylacrylate Salts
- Authors: Khachikyan R.D.1, Ovakimyan Z.G.1, Mikaelyan A.A.1, Paronikyan R.V.1, Stepanyan G.M.1
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Affiliations:
- A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
- Issue: Vol 51, No 10 (2018)
- Pages: 873-876
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244836
- DOI: https://doi.org/10.1007/s11094-018-1707-7
- ID: 244836
Cite item
Abstract
A series of β-p-toluylacrylate salts with various amines that retained the molecular fragment responsible for the antibacterial activity were synthesized. A new efficient method for obtaining β-aroylvinyl-1-pyridinium and -triphenylphosphonium bromides was proposed. Antibacterial testing showed that all investigated compounds possessed antibacterial properties.
About the authors
R. Dzh. Khachikyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Author for correspondence.
Email: khachikyanraya@gmail.com
Armenia, 26 Azatutyan Pr., 0014, Yerevan, 375014
Z. G. Ovakimyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: khachikyanraya@gmail.com
Armenia, 26 Azatutyan Pr., 0014, Yerevan, 375014
A. A. Mikaelyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: khachikyanraya@gmail.com
Armenia, 26 Azatutyan Pr., 0014, Yerevan, 375014
R. V. Paronikyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: khachikyanraya@gmail.com
Armenia, 26 Azatutyan Pr., 0014, Yerevan, 375014
G. M. Stepanyan
A. L. Mnjoyan Institute of Fine Organic Chemistry, Scientific and Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia
Email: khachikyanraya@gmail.com
Armenia, 26 Azatutyan Pr., 0014, Yerevan, 375014