Мақаланы E-mail арқылы жіберу Prospects of a Search for Kappa-Opioid Receptor Agonists with Analgesic Activity (Review)
- Авторлар: Zaitseva N.I.1, Galan S.E.1, Pavlova L.A.1
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Мекемелер:
- Research Institute of Pharmacy, I. M. Sechenov First Moscow State Medical University
- Шығарылым: Том 51, № 10 (2018)
- Беттер: 843-851
- Бөлім: Molecular-Biological Problems of Drug Design and Mechanism of Drug Action
- URL: https://journals.rcsi.science/0091-150X/article/view/244828
- DOI: https://doi.org/10.1007/s11094-018-1703-y
- ID: 244828
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Аннотация
Current approaches to the search for new kappa-opioid receptor (κ-OR) agonists with potential analgesic activity are reviewed. Agents with peripheral activity and biased agonists are most promising for development. Signal events initiated by κ-OR activation are considered. Chemical structures of presently known κ-OR agonists are presented.
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Авторлар туралы
N. Zaitseva
Research Institute of Pharmacy, I. M. Sechenov First Moscow State Medical University
Хат алмасуға жауапты Автор.
Email: nzaitseva@gmail.com
Ресей, 8/2 Trubetskaya St., Moscow, 119991
S. Galan
Research Institute of Pharmacy, I. M. Sechenov First Moscow State Medical University
Email: nzaitseva@gmail.com
Ресей, 8/2 Trubetskaya St., Moscow, 119991
L. Pavlova
Research Institute of Pharmacy, I. M. Sechenov First Moscow State Medical University
Email: nzaitseva@gmail.com
Ресей, 8/2 Trubetskaya St., Moscow, 119991
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