电邮这篇文章 Optimization of Drug Administration Dosage Regimen Considering Chronorhythms and Desynchronosis of Gastrointestinal-Tract Organs
- 作者: Bunyatyan N.D.1,2, Drogovoz S.M.3, Kononenko A.V.3, Olefir Y.V.1,2, Prokof’ev A.B.1,2
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隶属关系:
- I. M. Sechenov First Moscow State Medical University
- Scientific Center for Expert Evaluation of Medicinal Products, Ministry of Health of the Russian Federation
- National University of Pharmacy
- 期: 卷 51, 编号 8 (2017)
- 页面: 695-697
- 栏目: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244759
- DOI: https://doi.org/10.1007/s11094-017-1676-2
- ID: 244759
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详细
Medicinal effects on gastrointestinal-tract (GIT) organs under normal and pathological conditions are reviewed and analyzed. It is shown that rhythmic processes of digestive organs interact closely with the hierarchical structure of partial in vivo rhythms. This creates the prerequisites for prescribing medicines for GIT disorders considering individual in vivo chronorhythms and drug pharmacokinetic profiles.
作者简介
N. Bunyatyan
I. M. Sechenov First Moscow State Medical University; Scientific Center for Expert Evaluation of Medicinal Products, Ministry of Health of the Russian Federation
Email: chem@folium.ru
俄罗斯联邦, Moscow, 119991; Moscow, 127051
S. Drogovoz
National University of Pharmacy
Email: chem@folium.ru
乌克兰, Kharkiv, 61000
A. Kononenko
National University of Pharmacy
Email: chem@folium.ru
乌克兰, Kharkiv, 61000
Yu. Olefir
I. M. Sechenov First Moscow State Medical University; Scientific Center for Expert Evaluation of Medicinal Products, Ministry of Health of the Russian Federation
Email: chem@folium.ru
俄罗斯联邦, Moscow, 119991; Moscow, 127051
A. Prokof’ev
I. M. Sechenov First Moscow State Medical University; Scientific Center for Expert Evaluation of Medicinal Products, Ministry of Health of the Russian Federation
Email: chem@folium.ru
俄罗斯联邦, Moscow, 119991; Moscow, 127051
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