Biologically Active Substances From Dropwort (Filipendula vulgaris) and Assessment of Their Antioxidant Properties


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Abstract

This study demonstrated the antioxidant activity of aqueous and aqueous-ethanolic (40%, 70%, 95%) extracts of the above-ground parts of the dropwort (Filipendula vulgaris Moench) in relation to the process of electroreduction of oxygen. Antioxidant properties were more marked in the more lipophilic dropwort extract. The lipophilic fraction of the aqueous extract (extracted with ethyl acetate) had marked antioxidant activity, and its efficacy was greater than those of dihydroquercetin and ascorbic acid, and this resulted from the more complete extraction of total biologically active compounds of phenolic (simple phenols, flavonoids, hydroxycoumarins, phenolcarboxylic acids) and triterpene (acids, saponins) nature, as well as amino acids.

About the authors

I. V. Shilova

E. D. Goldberg Science Research Institute of Pharmacology and Regenerative Medicine; Tomsk State National Research University

Author for correspondence.
Email: dygaiam@pharmso.ru
Russian Federation, 3 Lenin Prospekt, Tomsk, 634028; 36 Lenin Prospekt, Tomsk, 634050

E. I. Korotkova

Tomsk National Research Polytechnic University

Email: dygaiam@pharmso.ru
Russian Federation, 30 Lenin Prospekt, Tomsk, 634050


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