Toxic and Immunomodulatory Properties of an Iron(II) Coordination Complex of Isoleucyltryptophan Dipeptide
- Autores: Kholnazarov B.M.1,2, Bunyatyan N.D.3,1, Olefir Y.V.3,1, Bobizoda G.M.2, Prokof’ev A.B.3,1
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Afiliações:
- Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation
- Sadriddin Aini Tajik State Pedagogical University
- I. M. Sechenov First Moscow State Medical University
- Edição: Volume 51, Nº 6 (2017)
- Páginas: 453-455
- Seção: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244650
- DOI: https://doi.org/10.1007/s11094-017-1632-1
- ID: 244650
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Resumo
Results from toxicological and pharmacological studies of the iron(II) coordination complex of the immunoactive dipeptide isoleucyltryptophan (timofer) were presented. It was established that timofer was practically nontoxic and exhibited high immunostimulatory activity when combined with viral and bacterial vaccines.
Sobre autores
B. Kholnazarov
Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation; Sadriddin Aini Tajik State Pedagogical University
Email: chem@folium.ru
Rússia, Moscow, 127051; Dushanbe, 733740
N. Bunyatyan
I. M. Sechenov First Moscow State Medical University; Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation
Email: chem@folium.ru
Rússia, Moscow, 119991; Moscow, 127051
Yu. Olefir
I. M. Sechenov First Moscow State Medical University; Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation
Email: chem@folium.ru
Rússia, Moscow, 119991; Moscow, 127051
G. Bobizoda
Sadriddin Aini Tajik State Pedagogical University
Email: chem@folium.ru
Tajiquistão, Dushanbe, 733740
A. Prokof’ev
I. M. Sechenov First Moscow State Medical University; Scientific Centre for Expert Evaluation of Medicinal Products, Ministry of Public Health of the Russian Federation
Email: chem@folium.ru
Rússia, Moscow, 119991; Moscow, 127051
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