Synthesis and Characterization of Poly(DL-Lactic Acid) Nanoparticles Loaded with the Antituberculosis Drug Isoniazid

M. Zh. Burkeev; E. M. Tazhbaev; L. Zh. Zhaparova; N. K. Zhappar; T. S. Zhumagalieva

doi:10.1007/s11094-016-1500-4

Synthesis and Characterization of Poly(DL-Lactic Acid) Nanoparticles Loaded with the Antituberculosis Drug Isoniazid

Authors: Burkeev M.Z.¹, Tazhbaev E.M.¹, Zhaparova L.Z.¹, Zhappar N.K.², Zhumagalieva T.S.¹
Affiliations:
1. E. A. Buketov Karaganda State University
2. Biomedpreparat Scientific-Analytical Center
Issue: Vol 50, No 9 (2016)
Pages: 608-611
Section: Drug Synthesis Methods and Manufacturing Technology
URL: https://journals.rcsi.science/0091-150X/article/view/244447
DOI: https://doi.org/10.1007/s11094-016-1500-4
ID: 244447

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Abstract

The possibility of creating a new dosage form of the antituberculosis drug isoniazid using nanoparticles of the polymer poly(DL-lactic acid) was studied. It was shown that nanoprecipitation was promising for preparing nanoparticles and loading them with drugs.