Email this article Vinpocetine Release From a Microencapsulated Form
- Authors: Polkovnikova Y.A.1, Slivkin A.I.1
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Affiliations:
- Voronezh State University
- Issue: Vol 50, No 8 (2016)
- Pages: 553-555
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244435
- DOI: https://doi.org/10.1007/s11094-016-1488-9
- ID: 244435
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Abstract
Microencapsulated vinpocetine was produced by liquid—liquid dispersion using a mixture of beeswax and cocoa oil in a 3:2 ratio as the carrier. The dispersion media were purified H2O and sodium carboxymethylcellulose (Na-CMC) solution (2%). Drug release from the microcapsules was studied in vitro as a function of microcapsule size, shell material, and dispersion medium. The best characteristics were observed for microcapsules with a hydrophobic coating containing beeswax and cocoa oil in a 3:2 ratio of size 0.5 – 1 mm that were produced in Na-CMC solution (2%).
About the authors
Yu. A. Polkovnikova
Voronezh State University
Author for correspondence.
Email: juli-polk@mail.ru
Russian Federation, 3 Studencheskaya St., Voronezh, 394006
A. I. Slivkin
Voronezh State University
Email: juli-polk@mail.ru
Russian Federation, 3 Studencheskaya St., Voronezh, 394006
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