Email this article Development of Manufacturing Technology for Prolonged-Release Oral Amben Preparation
- Authors: Nifontova G.O.1,2, Krechetov S.P.1, Korostylev E.V.3, Akhmetzyanova A.R.4, Krasnyuk I.I.2
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Affiliations:
- Life Sciences Center, Moscow Institute of Physics and Technology (Technical University)
- I. M. Sechenov First Moscow State Medical University
- Moscow Institute of Physics and Technology (Technical University)
- Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
- Issue: Vol 50, No 8 (2016)
- Pages: 537-542
- Section: Drug Synthesis Methods and Manufacturing Technology
- URL: https://journals.rcsi.science/0091-150X/article/view/244432
- DOI: https://doi.org/10.1007/s11094-016-1485-z
- ID: 244432
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Abstract
Results from technology development for manufacturing an amben prolonged-release preparation based on a Kollidon SR hydrophobic polymer matrix were presented. It was shown that dry and wet granulation could improve the processing properties of mixtures for preparing tablets and provide the required amben release kinetics.
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About the authors
G. O. Nifontova
Life Sciences Center, Moscow Institute of Physics and Technology (Technical University); I. M. Sechenov First Moscow State Medical University
Author for correspondence.
Email: galya.nif@yandex.ru
Russian Federation, Moscow Oblast, Dolgoprudnyi, 141700; Moscow, 119991
S. P. Krechetov
Life Sciences Center, Moscow Institute of Physics and Technology (Technical University)
Email: galya.nif@yandex.ru
Russian Federation, Moscow Oblast, Dolgoprudnyi, 141700
E. V. Korostylev
Moscow Institute of Physics and Technology (Technical University)
Email: galya.nif@yandex.ru
Russian Federation, Moscow Oblast, Dolgoprudnyi, 141700
A. R. Akhmetzyanova
Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
Email: galya.nif@yandex.ru
Russian Federation, Moscow Oblast, Khimki, 141402
I. I. Krasnyuk
I. M. Sechenov First Moscow State Medical University
Email: galya.nif@yandex.ru
Russian Federation, Moscow, 119991
