Email this article Synthesis and Antibactericidal Activities of Amines and Imines Containing (Aza, Thio)Xanthene Rings
- Authors: Gorokhov V.Y.1, Makhova T.V.1
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Affiliations:
- D. N. Pryanishnikov Perm State Agricultural Academy
- Issue: Vol 50, No 8 (2016)
- Pages: 530-533
- Section: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244430
- DOI: https://doi.org/10.1007/s11094-016-1483-1
- ID: 244430
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Abstract
N-Aryl(hetaryl)methylidene-4-[9-(thio)xanthenyl]anilines, N-arylmethylidene-{4-(5H-chromeno[2,3-b]pyridin-5-yl)phenyl}amines, and N-aryl(hetaryl)methyl-4-[9-(thio)xanthenyl]anilines were synthesized via the reaction of imines and amines with xanthydrol, thioxanthydrol, and 1-azaxanthydrol and exhibited antibacterial activity with respect to S. aureus No. 906 and E. coli No. 1257. Six museum and five hospital microorganism strains and three compounds that exhibited earlier high biological activity against three cultures (S. aureus No. 906, E. coli No. 1257, and C. albicans No. 24433) were tested in an expanded study.
About the authors
V. Yu. Gorokhov
D. N. Pryanishnikov Perm State Agricultural Academy
Author for correspondence.
Email: gorokhovV.Yu@mail.ru
Russian Federation, 23 Petropavlovskaya St., Perm, Perm Krai, 614990
T. V. Makhova
D. N. Pryanishnikov Perm State Agricultural Academy
Email: gorokhovV.Yu@mail.ru
Russian Federation, 23 Petropavlovskaya St., Perm, Perm Krai, 614990
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