Email this article Mechanisms of Antiradical Activity of 2,3,5,6,8-Pentahydroxy-7-Ethyl-1,4-Naphthoquinone (A Review)
- Authors: Talalaeva O.S.1, Zverev Y.F.1, Bryukhanov V.M.1
-
Affiliations:
- Altai State Medical University, Ministry of Health of the Russian Federation
- Issue: Vol 50, No 6 (2016)
- Pages: 353-357
- Section: Molecular-Biological Problems of Drug Design and Mechanism of Drug Action
- URL: https://journals.rcsi.science/0091-150X/article/view/244393
- DOI: https://doi.org/10.1007/s11094-016-1450-x
- ID: 244393
Cite item
Open Access
Access granted
Subscription Access
Abstract
The role of the antioxidant properties of 2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone in the manifestation of its pharmacological effects is reviewed. Issues with pleiotropic cellular-molecular mechanisms of echinochrome A action are considered with emphasis on the unique antioxidant activity of 2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone. These properties in combination with a low destructive potential account for the prospects of expanding the therapeutic use of echinochrome A.
Keywords
About the authors
O. S. Talalaeva
Altai State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, Barnaul, Altai Krai, 656038
Ya. F. Zverev
Altai State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, Barnaul, Altai Krai, 656038
V. M. Bryukhanov
Altai State Medical University, Ministry of Health of the Russian Federation
Email: chem@folium.ru
Russian Federation, Barnaul, Altai Krai, 656038
