Email this article Formulation Development and Study of Prolonged Release from Amben Peroral Preparations Based on Hydrophobic Matrices
- Authors: Nifontova G.O.1,2, Dolotova O.V.1, Sarantseva I.V.1, Akhmetzyanova A.R.3, Krechetov S.P.1, Krasnyuk I.I.2
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Affiliations:
- Life Sciences Center, Moscow Institute of Physics and Technology
- Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
- I. M. Sechenov First Moscow State Medical University
- Issue: Vol 50, No 2 (2016)
- Pages: 90-95
- Section: Drug Synthesis Methods and Manufacturing Technology
- URL: https://journals.rcsi.science/0091-150X/article/view/244325
- DOI: https://doi.org/10.1007/s11094-016-1404-3
- ID: 244325
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Abstract
Results from research on formulation development and prolonged release of peroral 4-aminomethylbenzoic acid (amben) using hydrophobic lipid and polymer matrices are reported. It is shown that the amben release parameters considering its solubility at various pH values can be achieved by using the studied polymer hydrophobic matrices.
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About the authors
G. O. Nifontova
Life Sciences Center, Moscow Institute of Physics and Technology; Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
Author for correspondence.
Email: galya.nif@yandex.ru
Russian Federation, Dolgoprudnyi, Moscow Oblast; Khimki, Moscow Oblast, 141402
O. V. Dolotova
Life Sciences Center, Moscow Institute of Physics and Technology
Email: galya.nif@yandex.ru
Russian Federation, Dolgoprudnyi, Moscow Oblast
I. V. Sarantseva
Life Sciences Center, Moscow Institute of Physics and Technology
Email: galya.nif@yandex.ru
Russian Federation, Dolgoprudnyi, Moscow Oblast
A. R. Akhmetzyanova
I. M. Sechenov First Moscow State Medical University
Email: galya.nif@yandex.ru
Russian Federation, Moscow, 119991
S. P. Krechetov
Life Sciences Center, Moscow Institute of Physics and Technology
Email: galya.nif@yandex.ru
Russian Federation, Dolgoprudnyi, Moscow Oblast
I. I. Krasnyuk
Farmzashchita Research and Production Center, Federal Medico-Biological Agency of the Russian Federation
Email: galya.nif@yandex.ru
Russian Federation, Khimki, Moscow Oblast, 141402
