Email this article Quaternization of Methyl Picolinate with Some Phenacyl Bromides. Synthesis of DL-Baikiain Alkaloid
- Authors: Lomov D.A.1, Abramyants M.G.1, Zaporozhets O.O.1, Pekhtereva T.M.1
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Affiliations:
- L. M. Litvinenko Institute of Physical Organic and Coal Chemistry
- Issue: Vol 94, No 1 (2024)
- Pages: 105-112
- Section: Articles
- URL: https://journals.rcsi.science/0044-460X/article/view/258263
- DOI: https://doi.org/10.31857/S0044460X24010095
- EDN: https://elibrary.ru/HKQMKV
- ID: 258263
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Abstract
By fusing methyl picolinate with phenacyl bromides, the corresponding phenacyl salts were obtained, cyclization of which in acetic anhydride led to previously undescribed 3-aryl-1H-pyrido[2,1-c][1,4]oxazinium bromides. Reduction of the quaternary salts of methyl picolinate followed by acid hydrolysis leads to the alkaloid DL-baikiain.
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About the authors
D. A. Lomov
L. M. Litvinenko Institute of Physical Organic and Coal Chemistry
Author for correspondence.
Email: lomov_dmitrii@mail.ru
Russian Federation, Donetsk
M. G. Abramyants
L. M. Litvinenko Institute of Physical Organic and Coal Chemistry
Email: lomov_dmitrii@mail.ru
Russian Federation, Donetsk
O. O. Zaporozhets
L. M. Litvinenko Institute of Physical Organic and Coal Chemistry
Email: lomov_dmitrii@mail.ru
Russian Federation, Donetsk
T. M. Pekhtereva
L. M. Litvinenko Institute of Physical Organic and Coal Chemistry
Email: lomov_dmitrii@mail.ru
Russian Federation, Donetsk
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