Synthesis of new imidazolidin-2-ones based on the reaction of 1-(2,2-dimethoxyethyl)urea with C-nucleophiles
- Autores: Smolobochkin A.1, Kuznetsova E.1, Gazizov A.1, Burilov A.1, Pudovik M.1
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Afiliações:
- Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”
- Edição: Volume 93, Nº 6 (2023)
- Páginas: 835-839
- Seção: Articles
- URL: https://journals.rcsi.science/0044-460X/article/view/145059
- DOI: https://doi.org/10.31857/S0044460X23060021
- EDN: https://elibrary.ru/FJUKMS
- ID: 145059
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Resumo
The acid-catalyzed reaction of 1-(2,2-dimethoxyethyl)ureas with aromatic and heterocyclic nucleophiles leads to the formation of new imidazolidin-2-ones. The proposed method makes it quite easy to introduce the required pharmacophore group into position 4 of the imidazolidine cycle.
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Sobre autores
A. Smolobochkin
Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”
Email: smolobochkin@iopc.ru
E. Kuznetsova
Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”
A. Gazizov
Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”
A. Burilov
Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”
M. Pudovik
Arbuzov Institute of Organic and Physical Chemistry, Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences”
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