Interaction of the Bipyridyl Gold(III) Complex with Anions of Thiol-Containing Acids in Aqueous Solution

I. V. Mironov; Миронов И. В.; V. Yu. Kharlamova; Харламова В. Ю.; J. Hu; Ху Ц.

doi:10.31857/S0044457X22601651

Interaction of the Bipyridyl Gold(III) Complex with Anions of Thiol-Containing Acids in Aqueous Solution

Authors: Mironov I.V.¹, Kharlamova V.Y.¹, Hu J.²
Affiliations:
1. Nikolaev Institute of Inorganic Chemistry, Siberian Branch, Russian Academy of Sciences
2. Novosibirsk State University
Issue: Vol 68, No 3 (2023)
Pages: 342-348
Section: ФИЗИКОХИМИЯ РАСТВОРОВ
URL: https://journals.rcsi.science/0044-457X/article/view/136333
DOI: https://doi.org/10.31857/S0044457X22601651
EDN: https://elibrary.ru/JDZGEF
ID: 136333

Cite item

Full Text

Open Access
Restricted Access

Access granted
Restricted Access

Subscription Access

Abstract
About the authors
References
Supplementary files
Statistics

Abstract

The equilibria of stepwise substitution Au(bipy)
+ OH– = Au(bipy)ClOH+ + Cl– and Au(bipy)
+ 2OH– = Au(bipy)
+ 2Cl– in aqueous solution at T = 25°C and I = 0.2 M (NaCl), log β1 = 9.22, log β2 = 16.61 have been studied. For bipyridyl complexes Au(bipy)
(X = Cl, OH) at pH 2.0 and 7.4, redox interactions with anions of thiol-containing acids (glutathione, cysteine, thiomalate) have been studied. In all cases, at the initial stage, a rapid reduction of gold(III) to gold(I) was observed with the simultaneous release of bipyridyl. A detailed analysis of UV spectra showed that the main products of gold(III) reduction are highly stable gold(I) thiolate complexes. The presence of further slower steps depends on the initial ratio of thiol to gold.

Keywords

nitrogen-containing ligands, complexation, glutathione, cysteine, thiomalate

References

Brinas R.P., Hu M., Qian L. et al. // J. Am. Chem. Soc. 2008. V. 130. P. 975. https://doi.org/10.1021/ja076333e
Corthey G., Giovanetti L.J., Ramallo-Lopez J.M. et al. // ACS Nano. 2010. V. 4. P. 3413. https://doi.org/10.1021/nn100272q
Brown D.H., Smith W.E. // J. Chem. Soc., Dalton Trans. 1980. P. 217.
Gabbiani C., Casini A., Messori L. // Gold Bull. 2007. V. 40. P. 73. https://doi.org/10.1007/BF03215296
Radisavljević S., Petrović B. // Front. Chem. 2020. V. 8. P. 379. https://doi.org/10.3389/fchem.2020.00379
Alhoshani A., Sulaiman A.A.A., Sobeai H.M.A. et al. // Molecules. 2021. V. 26. P. 3973. https://doi.org/10.3390/molecules26133973
Mironov I.V., Kharlamova V.Yu. // Inorg. Chim. Acta. 2021. V. 525. P. 120500. https://doi.org/10.1016/j.ica.2021.120500
Миронов И.В., Харламова В.Ю. // Журн. неорган. химии. 2022. Т. 67. № 7. С. 972.
Nobili S., Mini E., Landini I. et al. // Med. Res. Rev. 2010. V. 30. № 3. P. 550. https://doi.org/10.1002/med.20168
Mironov I.V., Kharlamova V.Yu. // J. Solution Chem. 2020. V. 49. P. 583. https://doi.org/10.1007/s10953-020-00994-0
Ахмадуллина Н.С., Чураков А.В., Ретивов В.М и др. // Коорд. химия. 2012. Т. 38. № 9. С. 611.
Avdeeva V.V., Vologzhanina A.V., Kubasov A.S. et al. // Inorganics. 2022. V. 10. P. 99. https://doi.org/10.3390/inorganics10070099
Harned H.S., Owen B.B. The Physical Chemistry of Electrolytic Solutions. N.Y.: Reinhold, 1950.
Mironov I.V., Kharlamova V.Yu. // J. Solution Chem. 2018. V. 47. P. 511. https://doi.org/10.1007/s10953-018-0735-y
Jakusch T., Buglyó P., Tomaz A.I. et al. // Inorg. Chim. Acta. 2002. V. 339. P. 119. https://doi.org/10.1016/S0020-1693(02)00919-2
LeBlanc D.J., Smith R.W., Wang Z. et al. // J. Chem. Soc., Dalton Trans. 1997. V. 18. P. 3263. https://doi.org/10.1039/A700827I
Đurović M.D., Bugarčić Ž.D., Heinemann F.W., Eldik R. // Dalton Trans. 2014. V. 43. P. 3911. https://doi.org/10.1039/C3DT53140F
Liu Y., Tian H., Xu L. et al. // Int. J. Mol. Sci. 2019. V. 20. P. 5660. https://doi.org/10.3390/ijms20225660
Brown D.H., Paton M., Smith W.E. // Inorg. Chim. Acta. 1982. V. 66. P. L51.
Casini A., Kelter G., Gabbiani C. et al. // J. Biol. Inorg. Chem. 2009. V. 14. P. 1139. https://doi.org/10.1007/s00775-009-0558-9
Messori L., Marcon G., Orioli P. // Bioinorg. Chem. Appl. 2003. V. l. № 2. P. 177. https://doi.org/10.1155/S1565363303000141
Marcon G., Carotti S., Coronnello M. et al. // J. Med. Chem. 2002. V. 45. P. 1672. https://doi.org/10.1021/jm010997w