Clinical portrait of a patient with COVID-19. The experience of a multidisciplinary clinic
- 作者: Baimakanova G.1, Khatkov I.1, Dudina G.1, Chegodar A.1, Rumyantsev K.1, Sviridov F.1,2, Osipova A.1, Danishevich A.1, Noskova K.1, Pinashina E.1, Orlova N.1, Slezinger V.1, Chernova M.1, Tovstyko K.1, Bodunova N.1
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隶属关系:
- Loginov Moscow Clinical Scientific and Practical Center
- Bochkov Research Centre for Medical Genetics
- 期: 卷 93, 编号 11 (2021)
- 页面: 1283-1289
- 栏目: Original articles
- URL: https://journals.rcsi.science/0040-3660/article/view/98465
- DOI: https://doi.org/10.26442/00403660.2021.11.201191
- ID: 98465
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Aim. Evaluation of the clinical characteristics in patients with COVID-19.
Materials and methods. The article presents clinical and instrumental data of 1169 patients included in a single-center mixed study. Patients were tested for COVID-19 using polymerase chain reaction, computed tomography (CT), and antibody screening. Clinical history data were collected.
Results. In patients with confirmed COVID-19, lung damage and a positive test for antibodies were observed in 75.5 and 45.2% of cases, respectively. The most common symptoms of COVID-19 were: fever (73.2%), weakness, (72.7%) dry cough (62.8%) and shortness of breath (55.4%). Patients with CT-visualized lung lesions were more likely to have clinical symptoms and elevated levels of antibodies. Patients with chronic diseases of the endocrine system, circulatory system, and respiratory system had a more severe course of the disease (CT-1–4: 91.2–96.3%) than patients without chronic diseases (CT-1–4: 85,1%).
Conclusion. We have compiled a clinical profile of patients with COVID-19 and highlighted the most significant clinical characteristics corresponding to a more severe course of the disease. Our data showed that patients with chronic diseases require a personalized approach and the development of specific criteria for the diagnosis and treatment of COVID-19.
作者简介
Gulsara Baimakanova
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0001-8198-9313
д-р мед. наук, зав. отд-нием пульмонологии ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowIgor Khatkov
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0002-4088-8118
чл.-кор. РАН, д-р мед. наук, проф., дир. ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowGalina Dudina
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0001-9673-1067
д-р мед. наук, зав. отд-нием онкогематологии ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowAnzhelika Chegodar
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0001-7753-3698
врач клинико-лабораторной диагностики Центра персонализированной медицины ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowKonstantin Rumyantsev
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0003-3184-5439
канд. биол. наук, ст. науч. сотр. Центра персонализированной медицины ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowFilipp Sviridov
Loginov Moscow Clinical Scientific and Practical Center; Bochkov Research Centre for Medical Genetics
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0003-3767-9339
мл. науч. сотр. Центра персонализированной медицины ГБУЗ «МКНЦ им. А.С. Логинова», науч. сотр. лаб. мутагенеза ФГБНУ «МГНЦ им. акад. Н.П. Бочкова»
俄罗斯联邦, Moscow
Alena Osipova
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0001-9664-0931
мл. науч. сотр. Центра персонализированной медицины ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowAnastasiia Danishevich
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0002-3573-8342
врач-генетик Центра персонализированной медицины ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowKarina Noskova
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
канд. мед. наук, зав. клинико-диагностической лаб. ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowEvgeniia Pinashina
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0002-0223-2302
врач-ординатор ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowNataliia Orlova
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0002-9007-7911
зав. рентгенологическим отд-нием ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowViacheslav Slezinger
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0002-2049-4146
зам. глав. врача по санитарно-эпидемиологической работе ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowMarina Chernova
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0002-6127-1723
канд. мед. наук, зав. инфекционно-эпидемиологическим отд., врач-инфекционист ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowKarina Tovstyko
Loginov Moscow Clinical Scientific and Practical Center
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0003-1989-0333
администратор Центра персонализированной медицины ГБУЗ «МКНЦ им. А.С. Логинова»
俄罗斯联邦, MoscowNatalia Bodunova
Loginov Moscow Clinical Scientific and Practical Center
编辑信件的主要联系方式.
Email: n.bodunova@mknc.ru
ORCID iD: 0000-0002-3119-7673
канд. мед. наук, зав. Центром персонализированной медицины ГБУЗ «МКНЦ им. А.С. Логинова»
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