The effect of taking antibacterial therapy on the outpatient stage and outcomes of community-acquired pneumonia in Tomsk hospitals
- 作者: Vinokurova D.1, Kulikov E.1, Kobyakova O.2, Starovoytova E.1, Deev I.2, Fedosenko S.1, Chernogoryuk G.1, Chernysheva E.3, Yarovoy N.4
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隶属关系:
- Siberian State Medical University
- Russian Research Institute of Health
- Medical and Sanitary Unit №2
- Tomsk Regional Oncology Center
- 期: 卷 96, 编号 1 (2024)
- 页面: 11-16
- 栏目: Original articles
- URL: https://journals.rcsi.science/0040-3660/article/view/258636
- DOI: https://doi.org/10.26442/00403660.2024.01.202574
- ID: 258636
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Background. Community-acquired pneumonia (CAP) remains one of the most common diseases requiring urgent hospitalization, with a significant part of patients already receiving antibiotics before admission to the hospital.
Aim. To assess the relationship between outpatient antibacterial therapy and in-hospital mortality and the severity of the CAP.
Materials and methods. The retrospective study included the data of adult patients with CAP who were hospitalized in Tomsk from January 1 to December 31, 2017.
Results. Among 1412 patients, 22.2% received antibiotics before admission to the hospital, the proportion of deaths in this group was significantly lower – 3.8% compared with 10.6% among patients without antibiotic therapy (p<0.001). Subjects who received antibiotics on outpatient basis were less likely to require being in the intensive care unit and administering vasopressors, in contrast to patients without prior antibiotic therapy: 5.1 and 10.6% (p=0.003); 7.1 and 4.7% (p=0.018) respectively. In patients with severe CAP on a scale IDSA/ATS, only 11.8% of cases were detected with antibiotics before hospitalization, while in mild CAP the frequency of administration was 16.6% (p<0.001).
Conclusion. Ambulatory antibacterial therapy had a positive effect on the subsequent course and outcomes of CAP in a hospital setting. Patients had a predominantly mild course of the disease, needing for vasopressors, and being in the intensive care unit, but was not consistent with the need for invasive mechanical ventilation.
作者简介
Daria Vinokurova
Siberian State Medical University
Email: elena-starovoytova@yandex.ru
ORCID iD: 0000-0002-8422-8349
зав. факультетской терапевтической клиникой
俄罗斯联邦, TomskEvgeny Kulikov
Siberian State Medical University
Email: evgeny.s.kulikov@gmail.com
ORCID iD: 0000-0002-0088-9204
доктор медицинских наук, ректор
俄罗斯联邦, TomskOlga Kobyakova
Russian Research Institute of Health
Email: o.s.kobyakova@gmail.com
ORCID iD: 0000-0003-0098-1403
доктор медицинских наук, профессор, директор
俄罗斯联邦, MoscowElena Starovoytova
Siberian State Medical University
编辑信件的主要联系方式.
Email: elena-starovoytova@yandex.ru
ORCID iD: 0000-0002-4281-1157
Head of the Department of General Medical Practice and Outpatient Therapy
俄罗斯联邦, TomskIvan Deev
Russian Research Institute of Health
Email: deevia@mednet.ru
ORCID iD: 0000-0002-4449-4810
доктор медицинских наук, профессор, зам. директора по организации здравоохранения
俄罗斯联邦, MoscowSergey Fedosenko
Siberian State Medical University
Email: sergey.fedosenko@icloud.com
ORCID iD: 0000-0001-6655-3300
доктор медицинских наук, доцент, профессор кафедры общей врачебной практики и поликлинической терапии
俄罗斯联邦, TomskGeorgy Chernogoryuk
Siberian State Medical University
Email: chernogoryuk@yandex.ru
ORCID iD: 0000-0001-5780-6660
доктор медицинских наук, профессор кафедры госпитальной терапии с курсом реабилитации, физиотерапии и спортивной медицины
俄罗斯联邦, TomskEkaterina Chernysheva
Medical and Sanitary Unit №2
Email: cherniisheva69@gmail.com
ORCID iD: 0000-0002-0553-4410
врач
俄罗斯联邦, TomskNikolay Yarovoy
Tomsk Regional Oncology Center
Email: koly-yarovoy@yandex.ru
ORCID iD: 0000-0003-3619-6095
врач
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