Кишечная микробиота как фактор риска развития ожирения и сахарного диабета 2-го типа
- Авторы: Демидова Т.Ю.1, Лобанова К.Г.1, Ойноткинова О.Ш.1,2,3
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Учреждения:
- ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России
- ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»
- ГБУ «Научно-исследовательский институт организации здравоохранения и медицинского менеджмента» Департамента здравоохранения г. Москвы
- Выпуск: Том 92, № 10 (2020)
- Страницы: 97-104
- Раздел: Обзоры
- URL: https://journals.rcsi.science/0040-3660/article/view/50989
- DOI: https://doi.org/10.26442/00403660.2020.10.000778
- ID: 50989
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Кишечная микробиота (КМ) – это совокупность бактерий, заселяющих желудочно-кишечный тракт. КМ и ее активные метаболиты принимают участие в кишечном и печеночном глюконеогенезе, в синтезе инкретиновых гормонов, влияют на регуляцию аппетита. Таким образом, КМ и ее продукты жизнедеятельности участвуют в гомеостазе углеводов и жиров. Дисбаланс состава кишечной флоры резко увеличивает риск развития ожирения и сахарного диабета 2-го типа. В литературе имеются противоречивые данные о роли конкретных микроорганизмов в развитии метаболических нарушений. Необходимы дальнейшие исследования, основанные на выявлении отдельных видов бактерий и продуктов их жизнедеятельности, которые влияют на развитие ожирения и сахарного диабета 2-го типа.
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Татьяна Юльевна Демидова
ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России
Email: miss.sapog@mail.ru
ORCID iD: 0000-0001-6385-540X
SPIN-код: 9600-9796
Scopus Author ID: 7003771623
д.м.н., проф., зав. каф. эндокринологии лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И. Пирогова»
Россия, МоскваКристина Геннадьевна Лобанова
ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России
Автор, ответственный за переписку.
Email: miss.sapog@mail.ru
ORCID iD: 0000-0002-3656-0312
SPIN-код: 6044-1684
ассистент каф. эндокринологии лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И. Пирогова»
Россия, МоскваОльга Шонкоровна Ойноткинова
ФГБОУ ВО «Российский национальный исследовательский медицинский университет им. Н.И. Пирогова» Минздрава России; ФГБОУ ВО «Московский государственный университет им. М.В. Ломоносова»; ГБУ «Научно-исследовательский институт организации здравоохранения и медицинского менеджмента» Департамента здравоохранения г. Москвы
Email: miss.sapog@mail.ru
ассистент каф. эндокринологии лечебного фак-та ФГБОУ ВО «РНИМУ им. Н.И. Пирогова»
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