The first Russian multicenter non-interventional registry study to study the incidence of vitamin D deficiency and insufficiency in Russian Federation

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Abstract

Aim. To assess the incidence of vitamin D deficiency and insufficiency among the adult population living in the regions of the Russian Federation located at latitudes from 45 to 70º.

Materials and methods. Russian multicenter non-interventional registry study using the "cross-sectional" method.

Results. In this study, 72.1% of the examined have the status of vitamin D deficiency and insufficiency, while an adequate level was diagnosed in 27.8% of cases. When assessing the degree of vitamin D deficiency depending on the season, statistically significant differences (p<0.00001) were found between the periods: vitamin D deficiency or insufficiency was observed in 84.2% of autumn and in 62.4% of spring. The highest incidence of vitamin D deficiency and insufficiency was recorded in males compared with females (p=0.013, 79 and 70.3% respectively). Vitamin D deficiency is observed in young people in the age subgroup of 18–25 years (p<0.001, 54% in the study as a whole) much more often than in older people

Conclusion. The widespread high prevalence of vitamin D deficiency in the Russian Federation is not related to geographic region of residence, but to some extent depends on the season. The high-risk group for vitamin D deficiency and insufficiency is young men. The significant role of vitamin D in the human body justifies the need to supplement and clarify a single concept for the prevention, diagnosis and treatment of conditions associated with deficiency, so higher implementation of National Clinical Guidelines is needed.

About the authors

Lyudmila A. Suplotova

Tyumen State Medical University

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0001-9253-8075

д-р мед. наук, проф., проф. каф. терапии ИНПР с курсами эндокринологии, ультразвуковой и функциональной диагностики

Russian Federation, Tyumen

Valeria A. Avdeeva

Tyumen State Medical University

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0002-8642-9435

канд. мед. наук, ассистент каф. пропедевтической и факультетской терапии

Russian Federation, Tyumen

Ekaterina A. Pigarova

Endocrinology Research Centre

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0001-6539-466X

д-р мед. наук, вед. науч. сотр., дир. Института высшего и дополнительного профессионального образования

Russian Federation, Moscow

Liudmila Ya. Rozhinskaya

Endocrinology Research Centre

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0001-7041-0732

д-р мед. наук, проф., гл. науч. сотр. отд-ния нейроэндокринологии и остеопатий

Russian Federation, Moscow

Tatiana L. Karonova

Almazov National Medical Research Centre

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0002-1547-0123

д-р мед. наук, проф., гл. науч. сотр., рук. научно-исследовательской лаборатории клинической эндокринологии Института эндокринологии

Russian Federation, Saint Petersburg

Ekaterina A. Troshina

Endocrinology Research Centre

Author for correspondence.
Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0002-8520-8702

член-кор. РАН, д-р мед. наук, проф., зав. отд. терапевтической эндокринологии, зам. дир. по координации эндокринологической службы

Russian Federation, Moscow

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2. Fig. 1. Peak diagram of 25(OH)D concentrations by study periods.

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