The first Russian multicenter non-interventional registry study to study the incidence of vitamin D deficiency and insufficiency in Russian Federation

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Aim. To assess the incidence of vitamin D deficiency and insufficiency among the adult population living in the regions of the Russian Federation located at latitudes from 45 to 70º.

Materials and methods. Russian multicenter non-interventional registry study using the "cross-sectional" method.

Results. In this study, 72.1% of the examined have the status of vitamin D deficiency and insufficiency, while an adequate level was diagnosed in 27.8% of cases. When assessing the degree of vitamin D deficiency depending on the season, statistically significant differences (p<0.00001) were found between the periods: vitamin D deficiency or insufficiency was observed in 84.2% of autumn and in 62.4% of spring. The highest incidence of vitamin D deficiency and insufficiency was recorded in males compared with females (p=0.013, 79 and 70.3% respectively). Vitamin D deficiency is observed in young people in the age subgroup of 18–25 years (p<0.001, 54% in the study as a whole) much more often than in older people

Conclusion. The widespread high prevalence of vitamin D deficiency in the Russian Federation is not related to geographic region of residence, but to some extent depends on the season. The high-risk group for vitamin D deficiency and insufficiency is young men. The significant role of vitamin D in the human body justifies the need to supplement and clarify a single concept for the prevention, diagnosis and treatment of conditions associated with deficiency, so higher implementation of National Clinical Guidelines is needed.

作者简介

Lyudmila Suplotova

Tyumen State Medical University

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0001-9253-8075

д-р мед. наук, проф., проф. каф. терапии ИНПР с курсами эндокринологии, ультразвуковой и функциональной диагностики

俄罗斯联邦, Tyumen

Valeria Avdeeva

Tyumen State Medical University

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0002-8642-9435

канд. мед. наук, ассистент каф. пропедевтической и факультетской терапии

俄罗斯联邦, Tyumen

Ekaterina Pigarova

Endocrinology Research Centre

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0001-6539-466X

д-р мед. наук, вед. науч. сотр., дир. Института высшего и дополнительного профессионального образования

俄罗斯联邦, Moscow

Liudmila Rozhinskaya

Endocrinology Research Centre

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0001-7041-0732

д-р мед. наук, проф., гл. науч. сотр. отд-ния нейроэндокринологии и остеопатий

俄罗斯联邦, Moscow

Tatiana Karonova

Almazov National Medical Research Centre

Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0002-1547-0123

д-р мед. наук, проф., гл. науч. сотр., рук. научно-исследовательской лаборатории клинической эндокринологии Института эндокринологии

俄罗斯联邦, Saint Petersburg

Ekaterina Troshina

Endocrinology Research Centre

编辑信件的主要联系方式.
Email: dr.avdeeva@yahoo.com
ORCID iD: 0000-0002-8520-8702

член-кор. РАН, д-р мед. наук, проф., зав. отд. терапевтической эндокринологии, зам. дир. по координации эндокринологической службы

俄罗斯联邦, Moscow

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2. Fig. 1. Peak diagram of 25(OH)D concentrations by study periods.

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