Email this article Testing and validation of the Russian version of quality of life questionnaire in patients with GERD – GERD-HRQL
- Authors: Ionova T.I.1,2, Zinkovskaya A.V.2, Mayevskaya E.A.3, Nikitina T.P.1,2, Porfirieva N.M.2, Cheremushkina N.V.3, Shaburov R.I.3,4, Kucheryavyy Y.A.3,5, Maev I.V.6
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Affiliations:
- Saint Petersburg State University Hospital
- Multinational Center for Quality of Life Research
- Yevdokimov Moscow State University of Medicine and Dentistry
- Central Clinic Hospital “RZD-Medicine”
- Ilyinsky Hospital
- ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России
- Issue: Vol 92, No 12 (2020)
- Pages: 59-66
- Section: Articles
- URL: https://journals.rcsi.science/0040-3660/article/view/60257
- DOI: https://doi.org/10.26442/00403660.2020.12.200434
- ID: 60257
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Abstract
Aim. This study aimed to test the Russian version of GERD-HRQL in the focus group of patients with GERD, as well as to evaluate its psychometric properties – reliability, validity and sensitivity.
Materials and methods. The total of 57 patients with GERD (mean age – 45.8±12.4 years, 72% – women, 68% – patients with not erosive reflux disease, 84% had esophageal manifestations of GERD) were enrolled into the study. All the patients filled out the Russian version of GERD-HRQL and generic quality of life questionnaire RAND SF-36 during the routine visit to the gastroenterologist. According to the results of testing of GERD-HRQL, it was clear and easy to complete for patients and reflected the main concerns specific for GERD patients. The most frequent and bothersome symptoms/problems which interfered with quality of life in GERD patients were heartburn (100% of patients) and bloating (84% of patients). During the validation procedure, the high reliability and validity of the Russian version of GERD-HRQL were demonstrated. It was shown that the tool was sensitive both to changes over time and to clinically determined differences in patients’ status.
Results. The Total GERD-HRQL Score was significantly higher (worse quality of life) in the following groups: a) patients who had esophageal manifestations of GERB vs those without esophageal manifestations of GERB; b) patients with GERD complications vs those without GERD complications, c) patients with comorbidities of upper gastrointestinal tract vs without those comorbidities; d) patients with erosive esophagitis vs with non-erosive reflux disease (p<0.05).
Conclusion. The developed Russian version of the GERD-HRQL questionnaire proved to have high psychometric properties and may be used in the Russian population of GERD patients both in research studies and in a real clinical practice.
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##article.viewOnOriginalSite##About the authors
T. I. Ionova
Saint Petersburg State University Hospital; Multinational Center for Quality of Life Research
Email: tnikitina_74@mail.ru
ORCID iD: 0000-0002-9431-5286
д.б.н., проф., рук. отд., председатель совета
Russian Federation, Saint PetersburgA. V. Zinkovskaya
Multinational Center for Quality of Life Research
Email: tnikitina_74@mail.ru
ORCID iD: 0000-0002-7028-0496
специалист по биостатистике
Russian Federation, Saint PetersburgE. A. Mayevskaya
Yevdokimov Moscow State University of Medicine and Dentistry
Email: tnikitina_74@mail.ru
ORCID iD: 0000-0002-3323-3279
к.м.н., ассистент каф.
Russian Federation, MoscowT. P. Nikitina
Saint Petersburg State University Hospital; Multinational Center for Quality of Life Research
Author for correspondence.
Email: tnikitina_74@mail.ru
ORCID iD: 0000-0002-8279-8129
к.м.н., врач-методист, рук. отд.
Russian Federation, Saint PetersburgN. M. Porfirieva
Multinational Center for Quality of Life Research
Email: tnikitina_74@mail.ru
ORCID iD: 0000-0003-3329-2743
науч. сотр.
Russian Federation, Saint PetersburgN. V. Cheremushkina
Yevdokimov Moscow State University of Medicine and Dentistry
Email: tnikitina_74@mail.ru
ORCID iD: 0000-0002-6387-1001
к.м.н., ассистент
Russian Federation, MoscowR. I. Shaburov
Yevdokimov Moscow State University of Medicine and Dentistry; Central Clinic Hospital “RZD-Medicine”
Email: tnikitina_74@mail.ru
ORCID iD: 0000-0001-9741-0150
к.м.н., ассистент, глав. врач
Russian Federation, MoscowYu. A. Kucheryavyy
Yevdokimov Moscow State University of Medicine and Dentistry; Ilyinsky Hospital
Email: tnikitina_74@mail.ru
ORCID iD: 0000-0001-7760-2091
к.м.н., доц. каф., зав. отд-нием
Russian Federation, MoscowI. V. Maev
ФГБОУ ВО «Московский государственный медико-стоматологический университет им. А.И. Евдокимова» Минздрава России
Email: tnikitina_74@mail.ru
ORCID iD: 0000-0001-6114-564X
Yevdokimov Moscow State University of Medicine and Dentistry
Russian Federation, MoscowReferences
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