Email this article Whooping cough in different periods of pregnancy
- Authors: Popova O.P.1, Smetanina S.V.2, Antipyat N.A.2, Revazyan N.R.2, Skirda T.A.3
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Affiliations:
- Russian Medical Academy of Continuous Professional Education
- Infectious Clinical Hospital №1
- Gabrichevsky Moscow Research Institute of Microbiology and Epidemiology
- Issue: Vol 92, No 11 (2020)
- Pages: 13-16
- Section: Original articles
- URL: https://journals.rcsi.science/0040-3660/article/view/56912
- DOI: https://doi.org/10.26442/00403660.2020.11.000417
- ID: 56912
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Abstract
Aim. To study the clinical course, diagnosis of pertussis in pregnant women.
Materials and methods. Under observation were 25 pregnant women with whooping cough. The age structure was dominated by patients from 6 to 35 years old, amounting to 64%. At the time of hospitalization in 2 (8%) patients the gestation period corresponded to the first trimester, in 7 (28%) – II, in 9 (36%) – III. In 7 (28%) patients, the diagnosis of whooping cough was made during childbirth. The following methods were used to verify pertussis: bacteriological, PCR and serological (ELISA).
Results and discussion. Clinical analysis showed that pregnant women with pertussis who came to the hospital were admitted to hospital mainly in the late stages of the disease (at 4–5 week in 68.6% of cases). Pertussis infection in all cases was typical: in moderate form – 96%, mild – at 4%. In 64% of patients, whooping cough accompanied by other respiratory diseases, which were the main cause of development of bronchitis. The use of ELISA allowed to confirm the clinical diagnosis in 91.7% of patients.
Conclusion. The course of whooping cough in pregnant women is characterized by a typical symptom complex. To improve the verification of the diagnosis, it is advisable to use modern laboratory tests (PCR, ELISA).
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##article.viewOnOriginalSite##About the authors
O. P. Popova
Russian Medical Academy of Continuous Professional Education
Author for correspondence.
Email: doctorpopova@yandex.ru
ORCID iD: 0000-0002-1772-5978
д.м.н., проф. каф. детских инфекционных болезней
Russian Federation, MoscowS. V. Smetanina
Infectious Clinical Hospital №1
Email: doctorpopova@yandex.ru
к.м.н., глав. врач
Russian Federation, MoscowN. A. Antipyat
Infectious Clinical Hospital №1
Email: doctorpopova@yandex.ru
зам. глав. врача
Russian Federation, MoscowN. R. Revazyan
Infectious Clinical Hospital №1
Email: doctorpopova@yandex.ru
врач-инфекционист 6-го акушерского отд-ния
Russian Federation, MoscowT. A. Skirda
Gabrichevsky Moscow Research Institute of Microbiology and Epidemiology
Email: doctorpopova@yandex.ru
к.м.н., вед. науч. сотр. лаб. эпидемиологии кокковых инфекций
Russian Federation, MoscowReferences
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