Whooping cough in different periods of pregnancy


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Aim. To study the clinical course, diagnosis of pertussis in pregnant women.

Materials and methods. Under observation were 25 pregnant women with whooping cough. The age structure was dominated by patients from 6 to 35 years old, amounting to 64%. At the time of hospitalization in 2 (8%) patients the gestation period corresponded to the first trimester, in 7 (28%) – II, in 9 (36%) – III. In 7 (28%) patients, the diagnosis of whooping cough was made during childbirth. The following methods were used to verify pertussis: bacteriological, PCR and serological (ELISA).

Results and discussion. Clinical analysis showed that pregnant women with pertussis who came to the hospital were admitted to hospital mainly in the late stages of the disease (at 4–5 week in 68.6% of cases). Pertussis infection in all cases was typical: in moderate form – 96%, mild – at 4%. In 64% of patients, whooping cough accompanied by other respiratory diseases, which were the main cause of development of bronchitis. The use of ELISA allowed to confirm the clinical diagnosis in 91.7% of patients.

Conclusion. The course of whooping cough in pregnant women is characterized by a typical symptom complex. To improve the verification of the diagnosis, it is advisable to use modern laboratory tests (PCR, ELISA).

作者简介

O. Popova

Russian Medical Academy of Continuous Professional Education

编辑信件的主要联系方式.
Email: doctorpopova@yandex.ru
ORCID iD: 0000-0002-1772-5978

д.м.н., проф. каф. детских инфекционных болезней

俄罗斯联邦, Moscow

S. Smetanina

Infectious Clinical Hospital №1

Email: doctorpopova@yandex.ru

к.м.н., глав. врач

俄罗斯联邦, Moscow

N. Antipyat

Infectious Clinical Hospital №1

Email: doctorpopova@yandex.ru

зам. глав. врача

俄罗斯联邦, Moscow

N. Revazyan

Infectious Clinical Hospital №1

Email: doctorpopova@yandex.ru

врач-инфекционист 6-го акушерского отд-ния

俄罗斯联邦, Moscow

T. Skirda

Gabrichevsky Moscow Research Institute of Microbiology and Epidemiology

Email: doctorpopova@yandex.ru

к.м.н., вед. науч. сотр. лаб. эпидемиологии кокковых инфекций

俄罗斯联邦, Moscow

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