Successful treatment of a rare variant of mesangioproliferative glomerulonephritis with IgM deposits with Cyclosporin A
- Authors: Gurova D.V.1, Chebotareva N.V.1, Vinogradov A.A.2, Stavrovskaya E.V.1, Lysenko L.V.1
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Affiliations:
- Sechenov First Moscow State Medical University (Sechenov University)
- Lomonosov Moscow State University
- Issue: Vol 92, No 6 (2020)
- Pages: 73-75
- Section: Consensuns
- URL: https://journals.rcsi.science/0040-3660/article/view/34989
- DOI: https://doi.org/10.26442/00403660.2020.06.000673
- ID: 34989
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Abstract
We present a case with a rare variant of glomerulonephritis, IgM nephropathy, which occurs mainly with nephrotic syndrome. The clinical features of this variant of kidney damage are characterized; the pathogenetic and the transformation of this form of nephritis into focal segmental glomerulosclerosis are discussed. The development of severe nephrotic syndrome at the beginning of the disease, the formation of secondary steroid resistance have confirmed this hypothesis and have justified the treatment with cyclosporin A aimed at the recovery of the function of the podocyte with remission of nephritis.
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##article.viewOnOriginalSite##About the authors
Daria V. Gurova
Sechenov First Moscow State Medical University (Sechenov University)
Email: natasha_tcheb@mail.ru
ORCID iD: 0000-0001-8232-3679
студентка, Клиника им. Е.М. Тареева
Russian Federation, MoscowNatalia V. Chebotareva
Sechenov First Moscow State Medical University (Sechenov University)
Author for correspondence.
Email: natasha_tcheb@mail.ru
ORCID iD: 0000-0003-2128-8560
д.м.н., проф., каф. внутренних, профессиональных болезней и ревматологии, Клиника им. Е.М. Тареева
Russian Federation, MoscowAnatoliy A. Vinogradov
Lomonosov Moscow State University
Email: natasha_tcheb@mail.ru
ORCID iD: 0000-0001-7529-0215
клинический ординатор каф. внутренних болезней
Russian Federation, MoscowEkaterina V. Stavrovskaya
Sechenov First Moscow State Medical University (Sechenov University)
Email: natasha_tcheb@mail.ru
доц. каф. внутренних, профессиональных болезней и ревматологии, Клиника им. Е.М. Тареева
Russian Federation, MoscowLidia V. Lysenko
Sechenov First Moscow State Medical University (Sechenov University)
Email: natasha_tcheb@mail.ru
д.м.н. проф., каф. внутренних, профессиональных болезней и ревматологии, Клиника им. Е.М. Тареева
Russian Federation, MoscowReferences
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