Difficulties in Goodpasture's syndrome diagnosing


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Abstract

The article analyzes the diagnosis and treatment of anti-GBM antibody disease (Goodpasture's syndrome) - a rare, severe progressive disease, associated with anti-glomerular basement membrane antibody-induced pulmonary hemorrhage and glomerulonephritis. The main problem of this pathology is late diagnosis, resulted in ineffective treatment. The article provides current information on the epidemiology, etiology and pathogenesis, diagnosis, and treatment of Goodpasture’s syndrome, as well as clinical case of a patient with this rare disease.

About the authors

V I Podzolkov

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

д.м.н., зав. каф. факультетской терапии №2 лечебного фак-та, директор клиники факультетской терапии УКБ №4; ORCID: 0000-0002-0758-5609 Moscow, Russia

G K Makhnach

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

к.м.н., зав. пульмонологическим отд-нием УКБ №4 Moscow, Russia

T I Ishina

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

к.м.н., доцент каф. факультетской терапии № 2 Moscow, Russia

A B Ponomarev

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

к.м.н., доцент каф. патологической анатомии Moscow, Russia

I D Medvedev

I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)

Email: ivanmedvedev_123@mail.ru
к.м.н., доцент каф. факультетской терапии №2 лечебного фак-та Первого МГМУ им. И.М. Сеченова Минздрава России (Сеченовского Университета); тел.: 8(926)232-79-26; e-mail: ivanmedvedev123@mail.ru; ORCID: 0000-0003-4210-2841 Moscow, Russia

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